本文選題：組織切片 + 眼眶　； 參考：《天津醫(yī)科大學(xué)》2008年碩士論文

【摘要】： 研究目的:用斷層解剖學(xué)方法研究眼眶球后結(jié)構(gòu)的形態(tài)以及內(nèi)部重要結(jié)構(gòu)的相互關(guān)系,并進(jìn)行三維可視化研究,闡明球后結(jié)構(gòu)的空間位置關(guān)系。為臨床治療提供解剖學(xué)依據(jù)。 材料與方法:用石蠟包埋法對1例離體眶尖標(biāo)本進(jìn)行處理,采用冠狀位連續(xù)切片,層厚為10um,獲得眼眶球后結(jié)構(gòu)解剖斷面圖像數(shù)據(jù)集。并將同一頭顱標(biāo)本行T1WI、T2WI序列多方位MRI檢查以及高分辨CT橫斷、直接冠狀位掃描,觀察各層面的構(gòu)成形態(tài)以及相互關(guān)系。再將斷面結(jié)構(gòu)數(shù)據(jù)圖像經(jīng)Photoshop8.0軟件精確對位以及配準(zhǔn)后,應(yīng)用3D-DOCTOR軟件在計算機上分別對眼球、眼外肌、視神經(jīng)、眼動、靜脈及其分支等結(jié)構(gòu)進(jìn)行三維重建并立體顯示,獲得直觀的三維立體構(gòu)型。應(yīng)用該軟件自帶工具測量球后數(shù)據(jù)并與臨床腫瘤資料相結(jié)合,為臨床診治提供依據(jù)。 結(jié)果: 1.明確眼眶球后結(jié)構(gòu)的連續(xù)斷面結(jié)構(gòu)數(shù)據(jù)以及眼外肌、神經(jīng)、血管的關(guān)系,完成眼眶球后部分的數(shù)據(jù)測量和形態(tài)觀察。 2.將斷面圖像與相應(yīng)的CT、MRI圖像進(jìn)行對照研究,完成眼眶球后結(jié)構(gòu)斷面影像解剖結(jié)構(gòu)的對照觀察。 3.獲得完整的球后結(jié)構(gòu)的三維立體模型,明確球后神經(jīng)、血管以及眼外肌的空間位置關(guān)系,用于指導(dǎo)臨床。 結(jié)論:本試驗通過對眼眶球后結(jié)構(gòu)的斷層解剖學(xué)研究,著重探討眼眶球后內(nèi)部結(jié)構(gòu)的大小、形態(tài)學(xué)表現(xiàn),對影像學(xué)研究提供斷層解剖學(xué)依據(jù),同時為球后病變的診斷與鑒別診斷提供依據(jù)。此外獲得的球后結(jié)構(gòu)的三維立體模型,為計算機輔助虛擬手術(shù)和數(shù)字化模擬教學(xué)提供了良好的平臺。
[Abstract]:Objective: to study the relationship between the shape of the posterior orbital structure and the internal important structure by means of sectional anatomy, and to make a three-dimensional visualization study to clarify the spatial and positional relationship of the retroglobular structure. To provide anatomic basis for clinical treatment. Materials and methods: a case of isolated orbital apex was treated with paraffin embedded method. The image data set of anatomical section of the orbital retroglobus structure was obtained by coronal serial section with the thickness of 10 umps. The same head specimen was examined by multidirectional MRI and high resolution CT transection and coronal scan. The morphology of each plane and the relationship between them were observed. Then the cross-sectional structure data were accurately aligned and registered by Photoshop8.0 software, and 3D reconstruction and stereoscopic display of the structures of eyeball, extraocular muscle, optic nerve, eye movement, vein and its branches were carried out using 3D-DOCTOR software on the computer, respectively. An intuitive three-dimensional configuration is obtained. The software has been used to measure the back ball data and combined with the clinical tumor data to provide the basis for clinical diagnosis and treatment. Results: 1. The data of the continuous cross-sectional structure and the relationship among the extraocular muscles, nerves and blood vessels were determined, and the data of the posterior part of the orbital ball were measured and observed. 2. The cross-sectional images were compared with the corresponding CT MRI images to observe the anatomical structure of the orbital retroglobus structure. 3. A complete three-dimensional model of the retrobulbar structure was obtained, and the spatial relationship of the retroglobular nerve, blood vessels and the extraocular muscle was determined to guide the clinical practice. Conclusion: this study focuses on the size and morphology of the internal structure of the orbital ball through the sectional anatomical study of the orbital retroglobus structure, and provides the sectional anatomical basis for the imaging study. It also provides basis for diagnosis and differential diagnosis of Retrobulbar lesions. In addition, the three-dimensional model of the back-ball structure is obtained, which provides a good platform for computer-aided virtual surgery and digital simulation teaching.
【學(xué)位授予單位】：天津醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2008
【分類號】：R322;R319

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