本文選題：牙齒拔除　切入點(diǎn)：位點(diǎn)保存　出處：《中國(guó)醫(yī)科大學(xué)》2010年碩士論文

【摘要】： 目的 牙齒拔除后,缺牙區(qū)骨組織通常會(huì)發(fā)生不可預(yù)見(jiàn)性地吸收,造成種植區(qū)骨量不足,前牙美學(xué)區(qū)域唇頰側(cè)骨量喪失尤為明顯。在這種情況下,需要進(jìn)行必要的軟硬組織移植,才能確保牙種植體植入的成功。為了防止或減少牙拔除后牙槽嵴吸收的量,我們?cè)谘例X拔除后即刻采用種植位點(diǎn)保存技術(shù),目的是評(píng)估經(jīng)位點(diǎn)保存技術(shù)處理后牙槽窩組織形態(tài)計(jì)量學(xué)上的改變。 方法 選擇6條雜種犬,年齡平均8.2個(gè)月,體重平均16.8kg。拔除各自上、下頜兩側(cè)第二門齒,隨機(jī)分兩組,在一側(cè)即刻填入骨誘導(dǎo)活性材料(OAM),為位點(diǎn)保存實(shí)驗(yàn)組；另一側(cè)不作處理,為牙槽窩自然愈合對(duì)照組。術(shù)后3個(gè)月處死全部動(dòng)物,制取樣本,進(jìn)行影像學(xué)檢測(cè)。置入10%福爾馬林溶液固定,之后用金鋼砂片將各牙槽窩位點(diǎn)切開(kāi),在梯度乙醇內(nèi)脫水7天,甲基丙烯酸甲酯浸泡包埋。硬化后,用Leica SP 1600硬組織切片機(jī),自頰舌矢狀方向通過(guò)牙槽窩中線長(zhǎng)軸切開(kāi)標(biāo)本,制成80微米厚度切片,甲苯胺藍(lán)染色。最后,利用圖像分析進(jìn)行組織計(jì)量及形態(tài)的評(píng)估。 結(jié)果 全部位點(diǎn)創(chuàng)口均獲Ⅰ期愈合,黏膜完整無(wú)開(kāi)裂、色澤正常,未發(fā)現(xiàn)感染、壞疽及其它異常癥狀,所有位點(diǎn)骨量均有不同程度的吸收。實(shí)驗(yàn)組位點(diǎn)處輪廓豐滿,同一位點(diǎn)實(shí)驗(yàn)前后的高度吸收值、寬度吸收值、骨密度改變值分別是-1.3±0.4mm、-0.3士0.1mm、149.8±12.5,圖像分析顯示新骨所占面積平均值為(30.2±3.7)%,對(duì)照組位點(diǎn)處輪廓萎縮,頰側(cè)骨壁明顯坍塌,高度和寬度喪失顯著,同一位點(diǎn)實(shí)驗(yàn)前后的高度吸收值、寬度吸收值、骨密度改變值分別為-2.7±0.6mm、-1.1±0.2mm、114.7±9.5,新骨所占面積平均值為(9.3±2.0)%。實(shí)驗(yàn)組平均骨量吸收程度顯著低于對(duì)照組(P0.001)。 結(jié)論 1、牙齒拔除后,牙槽窩位點(diǎn)保存技術(shù)的應(yīng)用能明顯減少牙槽嵴萎縮吸收程度。 2、OAM對(duì)拔牙位點(diǎn)的保存效果良好。
[Abstract]:PurposeAfter tooth extraction, bone tissue in tooth deficiency area is usually absorbed unpredictably, which results in insufficient bone mass in planting area, especially in labial and buccal side of anterior teeth aesthetic region.In such cases, soft and hard tissue transplants are necessary to ensure the success of dental implants.In order to prevent or reduce the absorption of alveolar ridge after extraction, we used implant site preservation technique immediately after tooth extraction to evaluate the morphometric changes of alveolar fossa treated by locus preservation technique.MethodSix mongrel dogs were selected with an average age of 8.2 months and an average weight of 16.8 kg.The second incisors were extracted from each side of the mandible and were randomly divided into two groups. The osteoinductive material (OAM) was immediately filled in one side as the site for preservation in the experimental group, while the other side was untreated as the control group for natural healing of the alveolar fossa.All the animals were killed 3 months after operation.10% formalin solution was implanted and then each alveolar fossa was cut open with gold steel sand. After 7 days of dehydration in gradient ethanol methyl methacrylate was soaked and buried.After sclerosis, Leica SP 1600 hard tissue slicer was used to cut the specimens from the sagittal direction of the buccal tongue through the long axis of the midline of the alveolar fossa, and to make 80 micron thickness slices, which were stained with toluidine blue.Finally, image analysis is used to evaluate tissue measurement and morphology.ResultAll site wounds were healed in stage 鈪，

本文編號(hào)：1706793