發(fā)布時間：2018-04-03 20:30

  本文選題：牙齒拔除　切入點：位點保存　出處：《中國醫(yī)科大學》2010年碩士論文

【摘要】： 目的 牙齒拔除后,缺牙區(qū)骨組織通常會發(fā)生不可預見性地吸收,造成種植區(qū)骨量不足,前牙美學區(qū)域唇頰側骨量喪失尤為明顯。在這種情況下,需要進行必要的軟硬組織移植,才能確保牙種植體植入的成功。為了防止或減少牙拔除后牙槽嵴吸收的量,我們在牙齒拔除后即刻采用種植位點保存技術,目的是評估經(jīng)位點保存技術處理后牙槽窩組織形態(tài)計量學上的改變。 方法 選擇6條雜種犬,年齡平均8.2個月,體重平均16.8kg。拔除各自上、下頜兩側第二門齒,隨機分兩組,在一側即刻填入骨誘導活性材料(OAM),為位點保存實驗組；另一側不作處理,為牙槽窩自然愈合對照組。術后3個月處死全部動物,制取樣本,進行影像學檢測。置入10%福爾馬林溶液固定,之后用金鋼砂片將各牙槽窩位點切開,在梯度乙醇內脫水7天,甲基丙烯酸甲酯浸泡包埋。硬化后,用Leica SP 1600硬組織切片機,自頰舌矢狀方向通過牙槽窩中線長軸切開標本,制成80微米厚度切片,甲苯胺藍染色。最后,利用圖像分析進行組織計量及形態(tài)的評估。 結果 全部位點創(chuàng)口均獲Ⅰ期愈合,黏膜完整無開裂、色澤正常,未發(fā)現(xiàn)感染、壞疽及其它異常癥狀,所有位點骨量均有不同程度的吸收。實驗組位點處輪廓豐滿,同一位點實驗前后的高度吸收值、寬度吸收值、骨密度改變值分別是-1.3±0.4mm、-0.3士0.1mm、149.8±12.5,圖像分析顯示新骨所占面積平均值為(30.2±3.7)%,對照組位點處輪廓萎縮,頰側骨壁明顯坍塌,高度和寬度喪失顯著,同一位點實驗前后的高度吸收值、寬度吸收值、骨密度改變值分別為-2.7±0.6mm、-1.1±0.2mm、114.7±9.5,新骨所占面積平均值為(9.3±2.0)%。實驗組平均骨量吸收程度顯著低于對照組(P0.001)。 結論 1、牙齒拔除后,牙槽窩位點保存技術的應用能明顯減少牙槽嵴萎縮吸收程度。 2、OAM對拔牙位點的保存效果良好。
[Abstract]:PurposeAfter tooth extraction, bone tissue in tooth deficiency area is usually absorbed unpredictably, which results in insufficient bone mass in planting area, especially in labial and buccal side of anterior teeth aesthetic region.In such cases, soft and hard tissue transplants are necessary to ensure the success of dental implants.In order to prevent or reduce the absorption of alveolar ridge after extraction, we used implant site preservation technique immediately after tooth extraction to evaluate the morphometric changes of alveolar fossa treated by locus preservation technique.MethodSix mongrel dogs were selected with an average age of 8.2 months and an average weight of 16.8 kg.The second incisors were extracted from each side of the mandible and were randomly divided into two groups. The osteoinductive material (OAM) was immediately filled in one side as the site for preservation in the experimental group, while the other side was untreated as the control group for natural healing of the alveolar fossa.All the animals were killed 3 months after operation.10% formalin solution was implanted and then each alveolar fossa was cut open with gold steel sand. After 7 days of dehydration in gradient ethanol methyl methacrylate was soaked and buried.After sclerosis, Leica SP 1600 hard tissue slicer was used to cut the specimens from the sagittal direction of the buccal tongue through the long axis of the midline of the alveolar fossa, and to make 80 micron thickness slices, which were stained with toluidine blue.Finally, image analysis is used to evaluate tissue measurement and morphology.ResultAll site wounds were healed in stage 鈪，

本文編號：1706793