本文選題：理虛解郁方　切入點：五行音樂　出處：《遼寧中醫(yī)雜志》2015年08期 　論文類型：期刊論文

【摘要】：目的:觀察五行音樂聯(lián)合中藥理虛解郁方對慢性疲勞綜合征大鼠行為學(xué)的影響。方法:將清潔級SD雄性大鼠78只隨機分為正常對照組、模型組、理虛解郁方組、音樂組(按五行音樂:宮商角徵羽五調(diào)分為5組),中藥聯(lián)合音樂治療組(按五行音樂:宮商角徵羽五調(diào)分為5組,簡稱音藥組)每組6只。給予復(fù)合因素造模(慢性束縛、冷水游泳、夾尾激怒法),同時正常組、模型組予生理鹽水2 m L,理虛解郁方組及音藥組予中藥2 m L灌胃,音樂及音藥組同時接受五行音樂治療,連續(xù)30 d,觀察治療前后大鼠行為學(xué)(曠場實驗、鼠尾懸掛實驗、力竭游泳實驗)的變化。結(jié)果:1與正常組比較,模型組大鼠穿格次數(shù)、直立次數(shù)、掙扎次數(shù)減少,靜止時間延長,力竭游泳時間明顯縮短,差異有統(tǒng)計學(xué)意義(P0.05);2與模型組比較,中藥組力竭游泳時間明顯延長,掙扎次數(shù)、直立次數(shù)、穿格次數(shù)增加,靜止時間縮短,其差異均有統(tǒng)計學(xué)差異(P0.05)。各音樂組力竭游泳時間明顯延長;且角調(diào)組掙扎次數(shù)增加、靜止時間縮短,其差異有統(tǒng)計學(xué)意義(P0.05);各音藥組力竭游泳時間明顯延長,藥徵組直立次數(shù)、穿格次數(shù)、掙扎次數(shù)均增加,靜止時間縮短;藥角組穿格次數(shù)、及掙扎次數(shù)增加,藥宮組穿格次數(shù)增加,藥商組靜止時間縮短,藥羽組穿格次數(shù)、掙扎次數(shù)均增加,靜止時間縮短,差異均有統(tǒng)計學(xué)意義;3各組間比較,中藥組穿格次數(shù)較藥宮組、藥商組、藥羽組增加;藥角組、藥徵組較其對應(yīng)單純音樂組穿格次數(shù)增加,藥徵組直立次數(shù)增加,其差異有統(tǒng)計學(xué)意義。結(jié)論:五行音樂聯(lián)合中藥理虛解郁方對于緩解大鼠的軀體及精神疲勞有較為明顯的療效,角調(diào)、徵調(diào)提示有初步增效作用。
[Abstract]:Objective: to observe the effect of the combination of five elements of music on the behavior of rats with chronic fatigue syndrome. Methods: 78 SD male rats of clean grade were randomly divided into normal control group, model group and Li-deficiency Jieyu prescription group. The music group was divided into 5 groups according to the five elements music: gong Shang angle syndrome five tones, and the traditional Chinese medicine combined music treatment group (according to the five elements music: gong Shang angle feather five tones divided into 5 groups, abbreviated as the tone medicine group), each group had 6 rats in each group. Cold water swimming, tail irritation method, normal group, model group, normal saline 2 mL, lixiu Jiayu prescription group and phonetic medicine group were given 2 mL of traditional Chinese medicine, and music and tone medicine group were treated with five elements music at the same time. After 30 days of treatment, the changes of behavior (open field test, tail suspension test, exhaustive swimming test) were observed. Results compared with the normal group, the rats in the model group decreased the number of lattice piercing, the number of upright, and the times of struggle. Compared with the model group, the swimming time of the traditional Chinese medicine group was significantly prolonged, the times of struggle, the number of upright, the number of piercing increased, and the time of rest was shortened, compared with the model group, the time of swimming was prolonged, the time of exhaustive swimming was shortened, and the time of exhaustive swimming was obviously shortened, compared with the model group. All the differences were statistically significant (P 0.05). The time of exhaustive swimming was significantly prolonged in each music group, and the number of struggle increased and the rest time was shortened in the angle adjustment group, the difference was statistically significant (P 0.05), the swimming time of exhausted swimming in each sound medicine group was obviously prolonged, and the times of standing upright in the drug sign group were obviously prolonged. The number of piercing, the number of struggles and the number of struggles in the drug angle group increased, the rest time in the drug quotient group decreased, and the number of cases and struggles increased in the drug plume group, while the number of cases in the drug angle group and the number of struggles in the drug angle group increased, and the rest time of the drug quotient group decreased. The rest time was shortened, the difference was statistically significant. The number of cases in the Chinese medicine group was higher than that in the medicine palace group, the drug quotient group, the drug plume group, the drug angle group, the drug sign group, and the corresponding music group, and the number of cases in the traditional Chinese medicine group was higher than that in the corresponding pure music group. Conclusion: the combination of five elements music has obvious curative effect on relieving the physical and mental fatigue of rats. The angle adjustment and sign indicate that there is a preliminary synergistic effect.
【作者單位】： 上海中醫(yī)藥大學(xué)附屬岳陽中西醫(yī)結(jié)合醫(yī)院中醫(yī)內(nèi)科;上海中醫(yī)藥大學(xué);
【基金】：國家自然科學(xué)基金面上項目(81173227) 上海市衛(wèi)生局項目(30304115240) 國家中醫(yī)藥管理局十二五重點學(xué)科“治未病學(xué)科”項目 上海市三年中醫(yī)行動計劃項目(ZYSNXD-YL-CTXK) 岳陽醫(yī)院慢性疲勞綜合征重點�？平ㄔO(shè)項目
【分類號】：R285.5;R-332

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