本文選題：活性氮　切入點(diǎn)：活性氧　出處：《生物化學(xué)與生物物理進(jìn)展》2017年05期

【摘要】：以自由基為代表的小分子活性物質(zhì)對(duì)于維持生物體正常的生理功能起著不可或缺的作用,但在包括中風(fēng)的多種病理狀態(tài)下,過量的小分子活性物質(zhì)由于其高活性、強(qiáng)氧化性可對(duì)人體內(nèi)的組織器官造成嚴(yán)重?fù)p傷.活性氧和活性氮是兩種重要的小分子活性物質(zhì),并且活性氮在中風(fēng)的發(fā)病機(jī)制中的作用備受關(guān)注,是近年研究的熱點(diǎn)之一.本文就近年來活性氮在中風(fēng)中的生理性與病理性的作用進(jìn)行綜述及展望.
[Abstract]:Small molecular active substances, represented by free radicals, play an indispensable role in maintaining the normal physiological functions of organisms. However, in various pathological states, including stroke, excess small molecular active substances are due to their high activity. Reactive oxygen species and active nitrogen are two important small molecular active substances, and the role of active nitrogen in the pathogenesis of stroke has attracted much attention. This paper reviews the physiological and pathological roles of active nitrogen in stroke.
【作者單位】： 首都醫(yī)科大學(xué)13級(jí)長(zhǎng)學(xué)制臨床醫(yī)學(xué)系;首都醫(yī)科大學(xué)基礎(chǔ)醫(yī)學(xué)院藥理學(xué)系;
【基金】：國(guó)家自然科學(xué)基金(31570856,21375133) 北京市自然科學(xué)基金(5152005) 2016年北京市教育委員會(huì)科技計(jì)劃一般項(xiàng)目基金(KM201610025003) 首都醫(yī)科大學(xué)本科學(xué)生科研訓(xùn)練項(xiàng)目(7NZDS2015)資助~~
【分類號(hào)】：R743.3
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本文編號(hào)：1681104