N末端B型利鈉肽原與超聲心動圖及血?dú)夥治雎?lián)合應(yīng)用對急性左心衰患者診斷和預(yù)后的影響
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本文關(guān)鍵詞: N末端B型利鈉肽原 超聲心動圖 血?dú)夥治?急性左心衰 診斷 預(yù)后 出處:《蘇州大學(xué)》2014年碩士論文 論文類型:學(xué)位論文
【摘要】:目的:探討聯(lián)合運(yùn)用N末端B型利鈉肽原(N-terminal pro-B-typenatriuretic peptide,NT-proBNP)檢測、超聲心動圖及血?dú)夥治鰧毙宰笮乃ソ呋颊咴\斷價(jià)值及平均住院日和預(yù)后的影響。 方法:以我院2008年1月至2010年6月NT-proBNP檢測開展前收治的急性左心衰患者為A組(對照組1)(共96例),以我院2011年7月至2013年12月NT-proBNP檢測開展后收治的急性左心衰患者為B組(實(shí)驗(yàn)組)(共98例),并以我院2011年7月至2013年12月NT-proBNP檢測開展后因急性呼吸困難同時行NT-proBNP檢測、超聲心動圖及血?dú)夥治雠懦毙宰笮乃セ颊邽镃組(對照組2)(共54例)。記錄并分析后兩組的診斷數(shù)據(jù);對前兩組患者隨訪6個月,比較前兩組的平均住院日、再住院率、死亡率和人均住院費(fèi)用。 結(jié)果:聯(lián)合應(yīng)用NT-proBNP檢測、超聲心動圖及血?dú)夥治鲈\斷模式可取得93.4%對急性左心衰診斷準(zhǔn)確性,高于聯(lián)合應(yīng)用NT-proBNP、超聲心動圖診斷準(zhǔn)確性(90.1%)及單獨(dú)使用NT-proBNP檢測或超聲心動圖診斷準(zhǔn)確性(分別是82.8%、76.3%)。B組平均住院日8.2±0.9天短于A組11.1±0.8天(P0.05);B組再住院率9.2%、死亡率5.1%低于A組再住院率15.6%、死亡率9.4%(P0.05);B組平均住院費(fèi)用9324±462元低于A組12315±574元(P0.05)。 結(jié)論:聯(lián)合運(yùn)用NT-proBNP檢測、超聲心動圖及血?dú)夥治隹商岣呒毙宰笮乃ピ\斷準(zhǔn)確性,,并可降低急性左心衰患者平均住院日、改善預(yù)后并節(jié)省住院費(fèi)用。
[Abstract]:Objective: to investigate the effect of N-terminal natriuretic peptide N-terminal pro-B-typenatriuretic peptiden (NT-proBNPP) combined with echocardiography and blood gas analysis on the diagnosis, mean hospitalization days and prognosis of patients with acute left heart failure (ARF). Methods: from January 2008 to June 2010, patients with acute left heart failure (AHF) treated in our hospital from January 2008 to June 2010 were selected as group A (control group 1) (96 cases). The patients treated with NT-proBNP from July 2011 to July 2011 were treated with acute left heart failure (AHF). The patients in group B (experimental group, 98 cases) were examined with NT-proBNP after NT-proBNP examination was carried out in our hospital from July 2011 to December 2013 because of acute dyspnea. Echocardiography and blood gas analysis excluded patients with acute left heart failure as group C (control group, n = 54). The diagnostic data of the latter two groups were recorded and analyzed. The patients in the first two groups were followed up for 6 months to compare the average days of hospitalization and the rate of re-hospitalization in the first two groups. Mortality and hospital expenses per capita. Results: 93.4% diagnostic accuracy of acute left heart failure could be obtained by combined use of NT-proBNP, echocardiography and blood gas analysis. The diagnostic accuracy of echocardiography was 90.1% higher than that of combined use of NT-proBNP and NT-proBNP alone or echocardiography (82.8% respectively). The average day of hospitalization in group B was 8.2 鹵0.9 days shorter than that in group A (11.1 鹵0.8 days). The rehospitalization rate of group B was lower than that of group A (5.1%). The mortality rate was 5.1% lower than that of group A. The average hospitalization cost of group B was 9324 鹵462.It was lower than that of group A (12315 鹵574 yuan). Conclusion: combined use of NT-proBNP, echocardiography and blood gas analysis can improve the diagnostic accuracy of acute left heart failure, reduce the average hospitalization days of patients with acute left heart failure, improve the prognosis and save hospital expenses.
【學(xué)位授予單位】:蘇州大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2014
【分類號】:R541.6
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