急性腦卒中患者血液白細胞分類及神經(jīng)功能缺損與臨床預后的關(guān)系
發(fā)布時間:2018-01-31 01:37
本文關(guān)鍵詞: 急性腦卒中 白細胞分類 神經(jīng)功能缺損 出處:《中國老年學雜志》2017年11期 論文類型:期刊論文
【摘要】:目的探討急性腦卒中患者血液白細胞分類、神經(jīng)功能缺損與臨床預合的關(guān)系。方法 90例急性腦卒中患者均檢測血液中白細胞分類并采用美國國立衛(wèi)生院腦卒中量表(NIHSS)評價神經(jīng)功能,探討白細胞分類與神經(jīng)功能及預后的關(guān)系。結(jié)果死亡和殘疾組白細胞計數(shù)、中性粒細胞比例、淋巴細胞計數(shù)、單核細胞計數(shù)、中性粒細胞/淋巴細胞(N/L)比值均高于獨立生活組,死亡和殘疾組各時間點1、7、14 d NHISS評分均明顯低于獨立生活組(均P0.05),相關(guān)因素分析N/L水平(P=0.02)、NIHSS評分(P=0.015)是腦卒中患者死亡的獨立危險因素。結(jié)論急性腦卒中患者血液白細胞分類與臨床預后密切相關(guān)。
[Abstract]:Objective to study the classification of leukocyte in patients with acute stroke. Methods 90 patients with acute stroke were examined for the classification of leukocytes in their blood and the neurological function was evaluated by NIHSS (National Institutes of Health Stroke scale). Results the leukocyte count, neutrophil ratio, lymphocyte count and monocyte count in the dead and disabled groups were studied. The ratio of neutrophil / lymphocyte N / L was higher than that of independent living group. The scores of NHISS were significantly lower than those of the independent living group on the 14th day (P 0.05, P < 0.05). The correlation factor analysis showed that the level of N / L was significantly lower than that of the control group (P < 0.05). NIHSS score (P0.015) is an independent risk factor for death in patients with stroke. Conclusion the classification of leukocyte in patients with acute stroke is closely related to the clinical prognosis.
【作者單位】: 南陽市中心醫(yī)院神經(jīng)內(nèi)科;
【分類號】:R743.3
【正文快照】: 急性腦卒中是臨床常見的危急重癥,具有較高的病死率。腦梗死的主要發(fā)病原因是高血壓及動脈粥樣硬化[1,2]。腦卒中患者臨床預后不同,輕者可完全恢復自主能力,重癥可癱瘓甚至死亡[3]。血液中白細胞分類與機體炎癥反應(yīng)密切相關(guān),研究提示白細胞分類與腦卒中患者臨床預后密切相關(guān)[4,
本文編號:1477816
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