【摘要】：目的分析鮑曼不動桿菌院內(nèi)感染的臨床分布特征及耐藥率變遷，，為臨床合理用藥提供參考，減少細(xì)菌耐藥及提高清除率。 方法收集病原學(xué)培養(yǎng)結(jié)果為鮑曼不動桿菌感染的住院患者臨床資料,總結(jié)分析臨床分布特點；比較不同年度、不同科室菌株的耐藥率差別。 結(jié)果558株鮑曼不動桿菌標(biāo)本來源中痰所占比例最高，達(dá)70.07%。重癥監(jiān)護(hù)病房和燒傷科分離率最高。來自于ICU科室的菌株耐藥率較非ICU科室高。2007-2013本院耐藥率變化中，頭孢哌酮舒巴坦的耐藥率每年最低，整體耐藥率略高于全國CHINET監(jiān)測水平。 結(jié)論ICU病房鮑曼不動桿菌分離率和耐藥率高；分離出多重耐藥菌株的患者同期混合感染比例高。頭孢哌酮舒巴坦耐藥率最低，可作為感染的臨床首選藥物。
[Abstract]:Objective to analyze the clinical distribution and drug resistance rate of Acinetobacter baumannii nosocomial infection in order to provide reference for rational drug use, reduce bacterial resistance and improve clearance rate. Methods the clinical data of the inpatients infected with Acinetobacter baumannii were collected and the clinical distribution characteristics were analyzed. Results the percentage of sputum in 558 strains of Acinetobacter baumannii was the highest (70.07%). The isolation rate of intensive care unit and burn department was the highest. The drug resistance rate of the strains from the ICU department was higher than that from the non-ICU department. The resistance rate of cefoperazone sulbactam was the lowest every year and the overall drug resistance rate was slightly higher than that of the national CHINET monitoring level in the change of drug resistance rate in our hospital from 2007 to 2013. Conclusion the isolation rate and drug resistance rate of Acinetobacter baumannii were high in ICU ward, and the rate of mixed infection was higher in patients with multiple drug resistance strains. Cefoperazone sulbactam has the lowest resistance rate and can be used as the first choice for infection.
【學(xué)位授予單位】：廣西醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號】：R378

【參考文獻(xiàn)】

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1 習(xí)慧明;徐英春;朱德妹;汪復(fù);倪語星;孫景勇;孫自鏞;簡翠;胡云建;艾效曼;張泓;李萬華;賈蓓;黃文祥;王傳清;王愛敏;魏蓮花;吳玲;卓超;蘇丹虹;張朝霞;季萍;徐元宏;熊自忠;沈繼錄;單斌;杜艷;俞云松;楊青;;2010年中國CHINET鮑曼不動桿菌耐藥性監(jiān)測[J];中國感染與化療雜志;2012年02期

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