本文選題：Notch + 信號(hào)通道��； 參考：《廣東醫(yī)學(xué)》2015年04期

【摘要】：正Notch信號(hào)通道是一分布廣泛且高度保守的信號(hào)通路,參與干細(xì)胞早期分化,對(duì)細(xì)胞的命運(yùn)起決定性作用,并在多種人類(lèi)疾病的發(fā)生發(fā)展中起重要作用。骨髓間充質(zhì)干細(xì)胞(marrow mesenchymal stem cells,MSCs)來(lái)源于中胚層,具有多向分化潛能,在特定條件下可分化為成骨細(xì)胞、軟骨細(xì)胞、脂肪細(xì)胞、心肌細(xì)胞、肝細(xì)胞、神經(jīng)元等,是組織工程學(xué)中重要的種子細(xì)胞。近年來(lái)眾多研究表明Notch信號(hào)通道的活
[Abstract]:The Notch signaling pathway is a widely distributed and highly conserved signal pathway, which is involved in the early differentiation of stem cells, plays a decisive role in the fate of cells and plays an important role in the occurrence and development of various human diseases. Bone marrow mesenchymal stem cells (BMSCs) derived from mesoderm have the potential to differentiate into osteoblasts, chondrocytes, adipocytes, cardiomyocytes, hepatocytes, neurons and so on. Is an important seed cell in tissue engineering. In recent years, many studies have shown that Notch signaling pathway is active.
【作者單位】： 廣西醫(yī)科大學(xué)附屬口腔醫(yī)院頜面外科;
【基金】：國(guó)家自然科學(xué)基金資助項(xiàng)目(編號(hào):81360166,81160132)
【分類(lèi)號(hào)】：R329.2

【參考文獻(xiàn)】

相關(guān)期刊論文 前3條

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2 牛萍;趙月強(qiáng);黃星原;;骨髓間充質(zhì)干細(xì)胞體外增殖及分化過(guò)程中Notch信號(hào)的表達(dá)變化[J];基礎(chǔ)醫(yī)學(xué)與臨床;2011年11期

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本文編號(hào)：2111193