發(fā)布時間：2018-06-24 08:49

  本文選題：椎間盤突出 + 動物模型��； 參考：《中國中醫(yī)骨傷科雜志》2015年10期

【摘要】：正腰椎間盤突出癥是臨床常見病、多發(fā)病,發(fā)病率約為20%~30%[1].然而椎間盤突出癥的生物學(xué)機(jī)制尚不明確,構(gòu)建與人類疾病相關(guān)性、可比性較高的椎間盤突出的動物模型是研究該病的基礎(chǔ)和關(guān)鍵。近年來,國內(nèi)外報(bào)道的椎間盤突出模型分為在體模型和體外模型,而動物在體模型是基礎(chǔ)研究成果過渡到臨床所必須跨越的研究階段。1實(shí)驗(yàn)誘導(dǎo)椎間盤突出動物模型1.1直接損傷模型1.1.1終板損傷模型Moon等[2]通過在家兔椎體
[Abstract]:Positive lumbar disc herniation is a common clinical disease, the incidence is about 20% [1]. However, the biological mechanism of intervertebral disc herniation is still unclear. It is the basis and key to study the disease to construct animal model of intervertebral disc herniation which is related to human disease and comparable. In recent years, intervertebral disc herniation models reported at home and abroad are divided into in vivo model and in vitro model. The animal model in vivo is the research stage that must be crossed by the basic research results. 1. 1 the animal model of intervertebral disc herniation induced by experiment 1.1 direct injury model 1.1.1 end plate injury model Moon et al. [2] through the rabbit vertebra body.
【作者單位】： 上海中醫(yī)藥大學(xué);江蘇省蘇州市中醫(yī)醫(yī)院;
【基金】：國家自然基金項(xiàng)目(81473691)
【分類號】：R681.53;R-332

【參考文獻(xiàn)】

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本文編號：2060892