本文關(guān)鍵詞：腎胺酶的研究進(jìn)展及其在臨床的應(yīng)用　出處：《新醫(yī)學(xué)》2015年12期 　論文類型：期刊論文

  更多相關(guān)文章： 腎胺酶 胺氧化酶 心血管 腎臟

【摘要】：腎胺酶是一種黃素蛋白,主要由腎小管近端上皮細(xì)胞合成和分泌,另外在心臟、骨骼肌和小腸等也有少量表達(dá)。腎胺酶曾被認(rèn)為是一種能夠有效降解兒茶酚胺類的酶蛋白,并在人類疾病中起重要作用。隨著研究的深入,腎胺酶的晶體結(jié)構(gòu)、功能、作用機制及其與人類疾病的關(guān)系逐漸被認(rèn)識。該文對腎胺酶的結(jié)構(gòu)、生物特性及與人類相關(guān)疾病的關(guān)系等進(jìn)行了綜述,旨在為腎胺酶的進(jìn)一步研究提供參考。
[Abstract]:The renal aminase is a kind of flavin protein, which is synthesized and secreted mainly by the proximal epithelial cells of the renal tubules, as well as a small amount of expression in the heart, skeletal muscle and small intestine. Kidney aminase has been considered as an enzyme protein that can effectively degrade catecholamine and plays an important role in human disease. With the development of research, the crystal structure, function and mechanism of the renal aminase and its relationship with human disease are gradually recognized. This article reviews the structure and biological characteristics of the renal aminase, and its relationship with human related diseases. The aim is to provide a reference for the further study of the renal aminase.
【作者單位】： 廣州醫(yī)科大學(xué)附屬第一醫(yī)院腎內(nèi)科;
【分類號】：R363
【正文快照】： 腎臟除了維持機體體液和電解質(zhì)平衡以外,還是一個重要的內(nèi)分泌器官。因為腎臟替代治療無法完全復(fù)制腎臟的內(nèi)分泌功能,終末期腎病(ESRD)患者雖然進(jìn)行了腎臟替代治療,但并未減少其心血管并發(fā)癥的危險因素[1]。最初發(fā)現(xiàn)由腎臟分泌的生物活性物質(zhì)是腎素,然后是促紅細(xì)胞生成素,接著，

本文編號：1344509