【摘要】：目的探討功能康復(fù)訓(xùn)練聯(lián)合步長腦心通膠囊在腦梗死患者康復(fù)期的應(yīng)用效果。方法將146例腦梗死康復(fù)期患者分為對(duì)照組(n=73)與研究組(n=73),對(duì)照組在常規(guī)治療的基礎(chǔ)上給予早期功能康復(fù)鍛煉,研究組在對(duì)照組的基礎(chǔ)上給予步長腦心通治療,均以4周為1個(gè)療程,治療2個(gè)療程。觀察兩組患者治療前,治療4周、8周改良Barthel指數(shù)(MBI),Fugl-Meyer量表(FMA),ReJoyce手功能測試(RAHFT)評(píng)分,治療前、后BOLD-fMRI定量研究對(duì)側(cè)大腦皮質(zhì)初級(jí)運(yùn)動(dòng)區(qū)(M1區(qū))激活體積和激活強(qiáng)度。結(jié)果研究組治療4周、8周MBI、FMA、RAHFT評(píng)分與同期對(duì)照組比較均明顯升高(P0.05);治療后M1區(qū)激活體積、激活強(qiáng)度與同期對(duì)照組比較均明顯升高(P0.05)。結(jié)論步長腦心通可促進(jìn)腦功能重建,促進(jìn)神經(jīng)功能恢復(fù),改善上肢運(yùn)動(dòng)功能。
[Abstract]:Objective to investigate the effect of functional rehabilitation training combined with step-size Naoxintong capsule in patients with cerebral infarction. Methods 146 patients with cerebral infarction in rehabilitation stage were divided into two groups: control group (n = 73) and study group (n = 73). The control group was given early functional rehabilitation exercise on the basis of routine treatment, and the study group was given step-by-step Naoxintong treatment on the basis of control group. All patients were treated with 4 weeks as a course of treatment and 2 courses of treatment. Before treatment, 4 weeks and 8 weeks after treatment, the (RAHFT) score of the (FMA), ReJoyce hand function test of the modified Barthel index (MBI), Fugl-Meyer scale was observed in the two groups. The activation volume and intensity of primary motor area (M1) in contralateral cerebral cortex were quantitatively studied by post-BOLD-fMRI. Results the MBI,FMA,RAHFT scores of the study group were significantly higher than those of the control group at 4 and 8 weeks after treatment (P0.05), and the activation volume and intensity of M1 region after treatment were significantly higher than those of the same period control group (P0.05). Conclusion step-size Naoxintong can promote the reconstruction of brain function, promote the recovery of nerve function and improve the motor function of upper limb.
【作者單位】： 河南省濮陽市人民醫(yī)院神經(jīng)內(nèi)科;
【分類號(hào)】：R743.33

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