【摘要】：目的分析卒中患病時(shí)間對(duì)北京市老年人群認(rèn)知功能的影響。方法基于北京市慢病合并常見老年綜合征社區(qū)管理規(guī)范研究課題,采用橫斷面研究方法,自2013年7月至2014年12月通過多階段、隨機(jī)、分層的抽樣方法對(duì)北京市4個(gè)區(qū)縣(西城區(qū)、房山區(qū)、通州區(qū)、延慶縣)的老年人群進(jìn)行抽樣,共納入研究對(duì)象3 024名。采用問卷調(diào)查和臨床檢查獲取數(shù)據(jù),以簡(jiǎn)易精神狀態(tài)檢查量表(MMSE)評(píng)分為認(rèn)知功能的評(píng)價(jià)指標(biāo),依據(jù)MMSE量表評(píng)分情況,將研究對(duì)象分為認(rèn)知功能正常組(MMSE26分,1 878名)和認(rèn)知功能障礙組(MMSE≤26分,1 146例)。采用多因素Logistic回歸模型分析出血性卒中、缺血性卒中及無癥狀卒中的患病情況及患病時(shí)間對(duì)認(rèn)知功能的影響。結(jié)果經(jīng)校正性別、年齡、受教育程度、婚姻、吸煙、飲酒等混雜因素后,患病1~3年、4~1 0年、1 0年的出血性卒中患者發(fā)生認(rèn)知功能障礙的風(fēng)險(xiǎn)分別為未發(fā)生卒中人群的3.019(95%CI:0.974~9.361,P=0.056)、8.652(95%CI:2.924~25.601,P0.01)、1.104倍(95%CI:0.311~3.920,P=0.879);患病1~3年、4~10年、10年的缺血性卒中患者發(fā)生認(rèn)知功能障礙的風(fēng)險(xiǎn)分別為未發(fā)生卒中人群的1.000(95%CI:0.636~1.571,P=1.000)、1.874(95%CI:1.231~2.853,P=0.003)、2.439倍(95%CI:1.386~4.291,P=0.002)。出血性卒中患者患病4~10年及缺血性卒中患者患病4~10年、10年均為認(rèn)知功能障礙發(fā)生的危險(xiǎn)因素。結(jié)論對(duì)于卒中患者,卒中患病時(shí)間或長(zhǎng)期效應(yīng)對(duì)認(rèn)知功能有一定影響。
[Abstract]:Objective to analyze the effect of stroke time on cognitive function of elderly population in Beijing. Methods based on the research topic of community management standard of chronic diseases complicated with common senile syndrome in Beijing, a cross-sectional study was conducted from July 2013 to December 2014. The stratified sampling method was used to sample the elderly population in 4 districts of Beijing (Xicheng District, Fangshan District, Tongzhou District, Yanqing County). A total of 3 024 subjects were included in the study. The data were obtained by questionnaire and clinical examination. The (MMSE) score of mini-mental state examination scale was taken as the evaluation index of cognitive function. According to the score of MMSE scale, the subjects were divided into normal cognitive function group (MMSE26 score). There were 1 878 patients with cognitive impairment and 1 146 patients with cognitive impairment (MMSE 鈮，

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