阿托伐他汀聯(lián)合拜阿司匹林對缺血性腦血管病患者頸部動脈斑塊及血清OxLDL、hs-CRP的影響
[Abstract]:Objective to observe the efficacy and safety of Aspirin combined with Atto vastatin in the treatment of ischemic cerebrovascular disease. Methods from January 2013 to June 2014, 86 cases of ischemic cerebrovascular disease with carotid artery plaque confirmed by color Doppler ultrasonography were randomly divided into two groups. 43 cases in the control group were treated with Aspirin at the same time of basic treatment, while 43 cases in the observation group were treated with Atto vastatin on the basis of the treatment in the control group. After 12 months of treatment, the changes of serum oxidized low density lipoprotein (Ox LDL),) (Ox LDL), hypersensitive C-reactive protein (hs-CRP) and carotid artery thickness (IMT) were recorded. Results after 12 months of treatment, the Ox LDL,hs-CRP,IMT of the observation group was significantly lower than that of the control group (P0.05), and the Ox LDL,hs-CRP,IMT of the observation group was lower than that of the control group (P0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P0.05). Conclusion Aspirin combined with Atto vastatin can decrease the levels of Ox LDL and hs-CRP in patients with ischemic cerebrovascular disease and has a positive significance for the reversal of atherosclerotic plaque.
【作者單位】: 南充市第二人民醫(yī)院神經(jīng)內(nèi)科;
【分類號】:R743.3
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