眼震電圖和前庭誘發(fā)肌源電位在眩暈診斷的應(yīng)用分析
發(fā)布時間：2018-11-14 13:32
【摘要】：目的：研究眩暈患者的眼震視圖（VNG）及前庭誘發(fā)肌源電位（VEMP）的特性，通過與健康對照組的相應(yīng)檢測數(shù)據(jù)的對比，探討VNG和VEMP在眩暈疾病中的診斷價值。 研究對象及方法：對32例健康對照按不同的性別、年齡分布進(jìn)行VEMP、VNG檢測。對114例眩暈患者按眩暈的臨床表現(xiàn)分為真性眩暈和假性眩暈組進(jìn)行VNG、VEMP檢查，將其檢測數(shù)據(jù)與健康對照進(jìn)行對比，分析比較不同組別之間各項數(shù)據(jù)的差異。 結(jié)果：1．健康對照組不同性別、年齡組的VEMP單側(cè)耳P13、N23潛伏期，及雙耳耳間潛伏期差、耳間振幅差（IAD）、耳間不對稱率差異無統(tǒng)計學(xué)意義，P0.05；男性的VEMP振幅高于女性，組間差異有統(tǒng)計學(xué)意義，P0.05。不同性別間溫度試驗異常率差異無統(tǒng)計學(xué)意義，P0.05；老年組的溫度試驗異常率高于中年組，組間差異有統(tǒng)計學(xué)意義，P0.05。 2．真性眩暈的VEMP各波潛伏期較健康對照組延長，差異有統(tǒng)計學(xué)意義，P0.05。真性眩暈組VNG異常檢出率高于健康對照組，差異有統(tǒng)計學(xué)意義，P0.05。真性眩暈組的VEMP異常檢出率、VNG異常檢出率和IAD、耳間不對稱率差異無統(tǒng)計學(xué)意義，，P0.05。3．假性眩暈組的VEMP單側(cè)耳P13、N23潛伏期、VNG異常檢出率均高于健康對照組，組間差異有統(tǒng)計學(xué)意義，P0.05；假性眩暈組的VEMP異常檢出率與VNG異常檢出率差異無統(tǒng)計學(xué)意義，P0.05；假性眩暈組的雙耳耳間潛伏期差、IAD、耳間不對稱率差異無統(tǒng)計學(xué)意義，P0.05。4．真性眩暈的VEMP異常檢出率較假性眩暈增高，組間差異有統(tǒng)計學(xué)意義，P0.05。真性眩暈組的VNG異常檢出率與假性眩暈對比差異無統(tǒng)計學(xué)意義，P0.05。 結(jié)論：1.VNG和VEMP聯(lián)合應(yīng)用可作為眩暈鑒別診斷的輔助工具。2.VEMP在真性眩暈的診斷中有更高的敏感性。3.VNG可區(qū)分前庭周圍性和中樞性病變。4.VNG中的溫度試驗、位置試驗對于判斷半規(guī)管病變有特殊的意義。
[Abstract]:Objective: to study the characteristics of nystagmus view (VNG) and vestibular evoked myogenic potential (VEMP) in patients with vertigo, and to explore the diagnostic value of VNG and VEMP in vertigo by comparing with the corresponding data of healthy control group. Methods: VEMP,VNG was performed on 32 healthy controls according to different sex and age distribution. According to the clinical manifestation of vertigo, 114 cases of vertigo were divided into true vertigo group and false vertigo group by VNG,VEMP examination. The data were compared with the healthy control group, and the differences between different groups were analyzed. Results: 1. There was no significant difference in the latency of VEMP single lateral ear P13N23, the difference of interauricular latency and amplitude difference between (IAD), ears in healthy control group (P 0.05). The VEMP amplitude of male was higher than that of female, and the difference between groups was statistically significant (P 0.05). The abnormal rate of temperature test in the old group was higher than that in the middle age group, and the difference between the two groups was statistically significant (P 0.05). 2. The latency of VEMP waves in true vertigo group was longer than that in healthy control group (P 0.05). The positive rate of VNG abnormality in true vertigo group was higher than that in healthy control group (P 0.05). There was no significant difference in the detection rate of VEMP abnormality, VNG abnormality and asymmetry rate between IAD, ears in true vertigo group (P0.05.3). The latent period and VNG abnormality detection rate of VEMP single lateral ear in pseudo vertigo group were higher than those in healthy control group. The difference between groups was statistically significant (P0.05; There was no significant difference between VEMP abnormality and VNG abnormality in pseudo vertigo group (P 0.05). There was no significant difference in latency between ears and asymmetry rate of IAD, in false vertigo group (P0.05.4). The detection rate of VEMP abnormality in veritable vertigo group was higher than that in false vertigo group, and the difference between groups was statistically significant (P0.05). There was no significant difference in VNG abnormal detection rate between true vertigo group and false vertigo group (P 0.05). Conclusion: the combination of 1.VNG and VEMP can be used as an assistant tool for differential diagnosis of vertigo. 2.VEMP is more sensitive in the diagnosis of true vertigo. 3.VNG can distinguish vestibular peripheral and central lesions. Location test is of special significance for the diagnosis of semicircular canal lesions.
【學(xué)位授予單位】：福建醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號】：R742
本文編號：2331304
[Abstract]:Objective: to study the characteristics of nystagmus view (VNG) and vestibular evoked myogenic potential (VEMP) in patients with vertigo, and to explore the diagnostic value of VNG and VEMP in vertigo by comparing with the corresponding data of healthy control group. Methods: VEMP,VNG was performed on 32 healthy controls according to different sex and age distribution. According to the clinical manifestation of vertigo, 114 cases of vertigo were divided into true vertigo group and false vertigo group by VNG,VEMP examination. The data were compared with the healthy control group, and the differences between different groups were analyzed. Results: 1. There was no significant difference in the latency of VEMP single lateral ear P13N23, the difference of interauricular latency and amplitude difference between (IAD), ears in healthy control group (P 0.05). The VEMP amplitude of male was higher than that of female, and the difference between groups was statistically significant (P 0.05). The abnormal rate of temperature test in the old group was higher than that in the middle age group, and the difference between the two groups was statistically significant (P 0.05). 2. The latency of VEMP waves in true vertigo group was longer than that in healthy control group (P 0.05). The positive rate of VNG abnormality in true vertigo group was higher than that in healthy control group (P 0.05). There was no significant difference in the detection rate of VEMP abnormality, VNG abnormality and asymmetry rate between IAD, ears in true vertigo group (P0.05.3). The latent period and VNG abnormality detection rate of VEMP single lateral ear in pseudo vertigo group were higher than those in healthy control group. The difference between groups was statistically significant (P0.05; There was no significant difference between VEMP abnormality and VNG abnormality in pseudo vertigo group (P 0.05). There was no significant difference in latency between ears and asymmetry rate of IAD, in false vertigo group (P0.05.4). The detection rate of VEMP abnormality in veritable vertigo group was higher than that in false vertigo group, and the difference between groups was statistically significant (P0.05). There was no significant difference in VNG abnormal detection rate between true vertigo group and false vertigo group (P 0.05). Conclusion: the combination of 1.VNG and VEMP can be used as an assistant tool for differential diagnosis of vertigo. 2.VEMP is more sensitive in the diagnosis of true vertigo. 3.VNG can distinguish vestibular peripheral and central lesions. Location test is of special significance for the diagnosis of semicircular canal lesions.
【學(xué)位授予單位】：福建醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號】：R742
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