【摘要】：目的：分析MR腦灌注成像在青年大腦中動(dòng)脈狹窄預(yù)后評(píng)估中的價(jià)值 方法：回顧性分析于2011年1月至2012年1月于濟(jì)寧醫(yī)學(xué)院附屬醫(yī)院神經(jīng)內(nèi)科住院,癥狀為反復(fù)短暫性腦缺血發(fā)作,并經(jīng)DSA證實(shí)的單側(cè)大腦中動(dòng)脈狹窄或閉塞患者的臨床資料,患者年齡45歲,共計(jì)60名。隨機(jī)選取年齡、性別等匹配的健康查體者60名作為對(duì)照。根據(jù)DSA結(jié)果進(jìn)行大腦中動(dòng)脈狹窄程度分組,分為輕度狹窄(0—29%)組,中度狹窄(30—69%)組,重度狹窄或閉塞(70%以上)組,在TIA發(fā)作間歇期行磁共振腦灌注成像(PWI)檢查,記錄PWI參數(shù)。隨訪1—2年,病例組根據(jù)梗死分組,分為梗死組或非梗死組,根據(jù)PWI參數(shù)探討不同狹窄程度梗死組與非梗死組差異。 結(jié)果：1.單側(cè)MCA輕度狹窄組12例,梗死組與非梗死組狹窄區(qū)PWI參數(shù)無明顯差異。2.單側(cè)MCA中度狹窄組28例,狹窄區(qū)PWI提示梗死組rMTT、rTTP較非梗死組延遲。3.單側(cè)MCA重度狹窄或閉塞組20例,狹窄區(qū)PWI提示梗死組rCBV較非梗死組下降,rMTT、rTTP明顯延遲。 結(jié)論：1.PWI對(duì)MCA狹窄中度以上患者進(jìn)行預(yù)后評(píng)估較輕度狹窄意義大。 2.磁共振PWI快速,操作簡(jiǎn)單,患者易于耐受,能反映全腦組織微血管結(jié)構(gòu)的血流灌注情況,提供血流動(dòng)力學(xué)方面的信息,是評(píng)價(jià)大腦中動(dòng)脈狹窄預(yù)后的敏感指標(biāo)。
[Abstract]:Objective: to evaluate the value of MR perfusion imaging in evaluating the prognosis of middle cerebral artery stenosis in young adults. Methods: retrospective analysis was conducted in the Department of Neurology, affiliated Hospital of Jining Medical College, from January 2011 to January 2012. The clinical data of patients with recurrent transient ischemic attack and unilateral middle cerebral artery stenosis or occlusion confirmed by DSA were 60 patients aged 45 years. Sixty matched age, sex and other health examiners were randomly selected as controls. According to the results of DSA, middle cerebral artery stenosis was divided into three groups: mild stenosis (0-29%), moderate stenosis (30-69%), severe stenosis or occlusion (more than 70%). Mr perfusion imaging (PWI) was performed during the interictal period of TIA. Record the PWI parameter. The patients were divided into infarction group and non-infarction group according to infarction group. The difference between infarction group and non-infarction group was discussed according to PWI parameters. The result is 1: 1. There was no significant difference in PWI parameters between infarct group and non infarction group in 12 patients with mild stenosis of unilateral MCA. There were 28 cases with moderate stenosis of unilateral MCA. The rMTT,rTTP in the infarct group was delayed by 3. 3% than that in the non-infarct group by PWI. There were 20 patients with severe stenosis or occlusion of unilateral MCA. PWI in the narrow area indicated that the rCBV in the infarction group was lower than that in the non-infarction group, and rMTT,rTTP was significantly delayed. Conclusion: the prognostic value of 1.PWI in patients with moderate or more MCA stenosis is higher than that in mild stenosis. 2. 2. Magnetic resonance imaging (PWI) is a sensitive index for evaluating the prognosis of middle cerebral artery stenosis. It can reflect the blood perfusion of the microvascular structure of the whole brain and provide hemodynamic information.
【學(xué)位授予單位】：天津醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R743.3

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 夏爽,祁吉,倪紅艷,李鵬;腦星形細(xì)胞瘤的MR灌注成像研究[J];放射學(xué)實(shí)踐;2004年10期

2 李振英;朱惠萍;劉力;梁琳琳;;同型半胱氨酸與腦血管病相關(guān)因素分析[J];臨床神經(jīng)病學(xué)雜志;2006年01期

3 羅國(guó)君;杜玲;王云甫;何國(guó)厚;;糖尿病與非糖尿病性急性腦梗死患者腦血管狹窄程度的比較[J];臨床神經(jīng)病學(xué)雜志;2007年04期

4 王桂紅,王擁軍,姜衛(wèi)劍,杜彬,何耀,金e，

本文編號(hào)：2269998