高壓氧在成人煙霧病治療中的應(yīng)用
發(fā)布時(shí)間:2018-08-31 07:33
【摘要】:目的探討高壓氧(hyperbaric oxygen therapy,HBOT)在成人煙霧病治療中的應(yīng)用價(jià)值。方法回顧性納入2009年3月至2016年12月于首都醫(yī)科大學(xué)附屬?gòu)?fù)興醫(yī)院高壓氧科收治的成人煙霧病病人,分析其臨床資料,高壓氧治療后神經(jīng)功能變化,治療期間新發(fā)腦血管事件以及隨訪(fǎng)90 d的預(yù)后。神經(jīng)功能缺損采用美國(guó)國(guó)立衛(wèi)生研究院卒中量表(National Institutes of Health Stroke Scale,NIHSS),預(yù)后評(píng)分采用改良Rankin量表(Modified Rankin Scale,mRS)。結(jié)果共納入13例成人煙霧病病人,其中缺血型8例,出血型5例,缺血型中4例累及雙側(cè)大腦半球,4例累及一側(cè)半球,5例此次發(fā)病接受了顱內(nèi)血運(yùn)重建手術(shù),4例術(shù)后出現(xiàn)新發(fā)腦梗死。出血型中3例單純腦室出血,2例腦內(nèi)出血破入腦室,全部病人接受血腫清除和(或)腦室穿刺術(shù)。HBOT前所有病人神經(jīng)功能均嚴(yán)重受損,HBOT次數(shù)最少5次,最多40次,HBOT后12例病人臨床癥狀得到改善,無(wú)效1例,2例治療期間出現(xiàn)新發(fā)腦梗死,90 d預(yù)后良好10例(mRS≤3分)。結(jié)論 HBOT有效減輕成人煙霧病術(shù)后的臨床癥狀和改善其90 d預(yù)后,治療期間不明顯增加腦血管事件的發(fā)生。
[Abstract]:Objective to investigate the value of hyperbaric oxygen (hyperbaric oxygen therapy,HBOT) in the treatment of adult moyamoya disease. Methods the patients with adult moyamoya disease treated in the Department of Hyperbaric oxygen, affiliated Renaissance Hospital of Capital Medical University from March 2009 to December 2016 were retrospectively included. The clinical data and the changes of nerve function after hyperbaric oxygen therapy were analyzed. New cerebrovascular events during treatment and prognosis of 90 days follow-up. The neurologic impairment was evaluated by (National Institutes of Health Stroke Scale,NIHSS (National Institutes of Health Stroke scale) and by modified Rankin scale (Modified Rankin Scale,mRS). Results A total of 13 adult moyamoya disease patients were included, including 8 cases of ischemic type and 5 cases of blood type. In the ischemic type 4 cases involved bilateral cerebral hemispheres 4 cases involved unilateral hemispheres 5 cases underwent intracranial revascularization operation and 4 cases had new cerebral infarction after operation. In the blood group, 3 cases had intraventricular hemorrhage and 2 cases had intracerebral hemorrhage broken into the ventricle. All the patients underwent hematoma clearance and (or) ventricular puncture. All the patients had serious neurological impairment before the operation. The number of HBOT was at least 5 times. The clinical symptoms of 12 patients were improved after up to 40 times of HBOT, and the prognosis of 10 patients (mRS 鈮,
本文編號(hào):2214316
[Abstract]:Objective to investigate the value of hyperbaric oxygen (hyperbaric oxygen therapy,HBOT) in the treatment of adult moyamoya disease. Methods the patients with adult moyamoya disease treated in the Department of Hyperbaric oxygen, affiliated Renaissance Hospital of Capital Medical University from March 2009 to December 2016 were retrospectively included. The clinical data and the changes of nerve function after hyperbaric oxygen therapy were analyzed. New cerebrovascular events during treatment and prognosis of 90 days follow-up. The neurologic impairment was evaluated by (National Institutes of Health Stroke Scale,NIHSS (National Institutes of Health Stroke scale) and by modified Rankin scale (Modified Rankin Scale,mRS). Results A total of 13 adult moyamoya disease patients were included, including 8 cases of ischemic type and 5 cases of blood type. In the ischemic type 4 cases involved bilateral cerebral hemispheres 4 cases involved unilateral hemispheres 5 cases underwent intracranial revascularization operation and 4 cases had new cerebral infarction after operation. In the blood group, 3 cases had intraventricular hemorrhage and 2 cases had intracerebral hemorrhage broken into the ventricle. All the patients underwent hematoma clearance and (or) ventricular puncture. All the patients had serious neurological impairment before the operation. The number of HBOT was at least 5 times. The clinical symptoms of 12 patients were improved after up to 40 times of HBOT, and the prognosis of 10 patients (mRS 鈮,
本文編號(hào):2214316
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