血尿酸水平與大面積腦梗死的相關(guān)性研究
發(fā)布時(shí)間:2018-06-29 21:12
本文選題:大面積腦梗死 + 血尿酸; 參考:《青島大學(xué)》2014年碩士論文
【摘要】:目的:探討血尿酸水平與大面積腦梗死的相互關(guān)系。 方法:將我院新發(fā)大面積腦梗死患者95例設(shè)為病例組,將同期在我院健康體檢者95例設(shè)為對(duì)照組,兩組的性別和年齡相匹配。檢測(cè)血尿酸(BUA)、血糖(FPG)、甘油三酯(TG)、總膽固醇(TC)、低密度脂蛋白膽固醇(LDL-C)及梗死面積(再將大面積腦梗死根據(jù)梗死區(qū)直徑分①大梗死灶,梗死直徑為在50mm-70mm之間,②較大梗死灶,直徑在70mm-90mm之間,③特大梗死灶,直徑90mm以上三組),并對(duì)其進(jìn)行相關(guān)性分析。 結(jié)果:1.病例組BUA、FP、TG、TC、LDL-c均高于對(duì)照組,采用多因素分析(Logistic回歸分析),修正其它已確定的腦血管病危險(xiǎn)因素(如糖尿病、高血脂癥等)后,這種關(guān)聯(lián)依然存在。2.血尿酸水平與腦梗死面積呈正相關(guān)。 結(jié)論:高尿酸血癥是大面積腦梗死的獨(dú)立危險(xiǎn)因素,且腦梗死的面積與血尿酸水平呈正相關(guān)性。
[Abstract]:Objective: to study the relationship between serum uric acid level and large area cerebral infarction. Methods: a total of 95 patients with large area cerebral infarction in our hospital were divided into two groups: the control group (n = 95) and the control group (n = 95). The sex and age of the two groups were matched. Serum uric acid (Bua), blood glucose (FPG), triglyceride (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and infarct area were measured. The diameter of 3 large infarcts between 70mm-90mm and above three groups of diameter 90mm), and the correlation analysis was carried out. The result is 1: 1. The LDL-c levels of BUAFV TGG / TCN in the case group were higher than those in the control group. This association still existed after the multivariate analysis (logistic regression analysis) was used to correct other identified risk factors of cerebrovascular disease (such as diabetes mellitus, hyperlipidemia, etc.). The level of uric acid was positively correlated with the area of cerebral infarction. Conclusion: hyperuricemia is an independent risk factor for large area cerebral infarction, and the area of cerebral infarction is positively correlated with serum uric acid level.
【學(xué)位授予單位】:青島大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2014
【分類號(hào)】:R743.3
【參考文獻(xiàn)】
相關(guān)期刊論文 前3條
1 薛新紅;曲松濱;;尿酸與缺血性腦卒中的關(guān)系[J];中國(guó)老年保健醫(yī)學(xué);2006年04期
2 楊明功;章秋;郭延云;;老年高尿酸血癥與糖尿病[J];實(shí)用老年醫(yī)學(xué);2006年01期
3 季波;何龍錦;丁雪明;唐涌;;高尿酸血癥與急性腦梗死關(guān)系[J];現(xiàn)代醫(yī)藥衛(wèi)生;2006年04期
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