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  本文選題：顱內(nèi)靜脈竇血栓 + 靜脈性出血/梗死��； 參考：《福建醫(yī)科大學(xué)》2014年碩士論文

【摘要】：目的：探討顱內(nèi)靜脈竇血栓患者繼發(fā)腦實質(zhì)損傷（包括靜脈梗死或出血，，腦水腫等）可能存在的相關(guān)風(fēng)險因素（如血栓在靜脈竇中的范圍和位置，年齡，性別，起病至接受治療時間，病因），比較兩組患者臨床癥狀及預(yù)后差異。 方法：回顧性分析2009年12月至2014年1月于福建醫(yī)科大學(xué)附屬第一醫(yī)院住院治療的顱內(nèi)靜脈竇血栓的患者，經(jīng)顱腦MRI或CT證實，分為A組（未發(fā)現(xiàn)腦實質(zhì)損害），B組（存在腦實質(zhì)損害，表現(xiàn)為靜脈性出血、梗死或腦水腫等）組。收集患者的臨床資料、實驗室檢查及影像學(xué)資料，采用CVST評分量化靜脈竇中血栓分布及范圍，同時分別分析兩組患者之間的年齡、性別、病因、起病至治療時間是否與腦實質(zhì)損傷存在關(guān)聯(lián)。 結(jié)果：共入選患者54例，A組患者有27例，B組27例。A組（無腦實質(zhì)損害）CVST計分平均值：2.51，相對于B組（存在腦實質(zhì)損傷）CVST計分平均值：4.33，兩組比較有統(tǒng)計學(xué)意義（P0.05）.；A組患者起病時間166.07±382.32天，B組患者8.44±7.35天，兩組比較有統(tǒng)計學(xué)意義。而患者年齡、性別及病因分析，無統(tǒng)計學(xué)意義，并無證據(jù)說明可能對腦實質(zhì)損傷造成影響。 結(jié)論：CVST患者中，廣泛的靜脈竇內(nèi)血栓形成，急性起病者更容易出現(xiàn)腦實質(zhì)損傷。相對于無腦實質(zhì)損傷組患者，腦實質(zhì)損傷組往往臨床癥狀重。
[Abstract]:Objective: to investigate the possible risk factors associated with cerebral parenchymal injury (including venous infarction or hemorrhage, cerebral edema, etc.) in patients with intracranial venous sinus thrombosis, such as the extent and location of thrombosis in the venous sinus, age, sex, etc. The clinical symptoms and prognosis were compared between the two groups. Methods: the patients with intracranial venous sinus thrombosis treated in the first affiliated Hospital of Fujian Medical University from December 2009 to January 2014 were retrospectively analyzed and confirmed by MRI or CT. Group A (no cerebral parenchymal lesion was found) group B (with cerebral parenchyma lesion, including venous hemorrhage, infarction or cerebral edema, etc.). The clinical data, laboratory examination and imaging data of the patients were collected, and the distribution and extent of venous sinus thrombosis were quantified by CVST score. The age, sex and etiology of the two groups were analyzed respectively. Whether the time from onset to treatment is associated with brain parenchymal injury. Results: a total of 54 patients were enrolled in group A, 27 patients in group B, 27 patients in group A. (average score of CVST without brain parenchyma damage: 2.51), compared with group B (CVST score with cerebral parenchyma injury: average: 4.33), there was significant difference between the two groups (P 0.05). The onset time was 166.07 鹵382.32 days in group B and 8.44 鹵7.35 days in group B. There was statistical significance between the two groups. Age, sex and etiological analysis were not statistically significant, and there was no evidence of possible effects on brain parenchyma injury. Conclusion among the patients with CVST, extensive venous sinus thrombosis is found, and cerebral parenchymal injury is more likely to occur in patients with acute onset of CVST. Compared with the anencephalic injury group, the cerebral parenchymal injury group often has severe clinical symptoms.
【學(xué)位授予單位】：福建醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號】：R743.3

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本文編號：1977521