本文選題：尿毒癥 + 不安腿綜合征(RLS)��； 參考：《臨床醫(yī)藥文獻(xiàn)電子雜志》2016年52期

【摘要】：目的探討血液灌流聯(lián)合血液透析對(duì)尿毒癥不安腿綜合征(RLS)患者的療效。方法選取2013年4月~2014年4月我院腎內(nèi)科收治的尿毒癥不安腿綜合征患者40例作為研究對(duì)象,隨機(jī)將其分為對(duì)照組和觀察組,各20例。對(duì)照組單用血液透析治療,觀察組采用血液灌流聯(lián)合血液透析,比較兩組患者的療效、RLS評(píng)分、相關(guān)實(shí)驗(yàn)室指標(biāo)變化。結(jié)果觀察組治療有效率為95%,明顯高于對(duì)照組的75%,差異有統(tǒng)計(jì)學(xué)意義(P0.05);觀察組治療后RLS評(píng)分、β2-MG、i PTH明顯較對(duì)照組改善,差異有統(tǒng)計(jì)學(xué)意義(P0.05);觀察組低血壓、牙齦出血等并發(fā)癥發(fā)生率與對(duì)照組相比,差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論血液灌流聯(lián)合血液透析對(duì)尿毒癥不安腿綜合征療效良好,能有效清除血液中β2-MG、i PTH,減輕對(duì)周?chē)窠?jīng)功能影響,緩解癥狀,具有積極的臨床意義。
[Abstract]:Objective to investigate the effect of hemoperfusion combined with hemodialysis on patients with uremic restless leg syndrome (RLS). Methods from April 2013 to April 2014, 40 patients with uremic restless leg syndrome were randomly divided into control group and observation group. The control group was treated with hemodialysis alone, the observation group was treated with hemoperfusion combined with hemodialysis, and the RLS scores and related laboratory indexes were compared between the two groups. Results the effective rate of treatment in the observation group was 95%, which was significantly higher than that in the control group (75%), the difference was statistically significant (P 0.05), the RLS score and 尾 2-MGG PTH in the observation group were significantly improved than those in the control group (P 0.05), the hypotension in the observation group was significantly higher than that in the control group (P 0.05). The incidence of complications such as gingival hemorrhage was not significantly different from that of the control group (P 0.05). Conclusion Hemoperfusion combined with hemodialysis is effective in the treatment of uremic restless leg syndrome. It can effectively eliminate 尾 _ 2-MGG _ I PTH in blood, alleviate the influence on peripheral nerve function and relieve symptoms. It has positive clinical significance.
【作者單位】： 廈門(mén)大學(xué)附屬第一醫(yī)院心內(nèi)科;
【分類(lèi)號(hào)】：R692.5;R741

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