【摘要】：目的觀察華佗再造丸輔助治療急性腦梗的臨床療效。方法 85例急性腦梗死患者分為觀察組43例和對(duì)照組42例,兩組均采用常規(guī)臨床腦梗死治療方法,觀察組在此基礎(chǔ)上加服華佗再造丸,8 g/次,3次/d,兩組均治療1個(gè)月。比較兩組治療前后動(dòng)脈硬化指數(shù)(AIP)及神經(jīng)功能缺損程度(NIHSS評(píng)分),檢測(cè)兩組治療前后血清白細(xì)胞介素10(IL-10)、血清高同型半胱氨酸(Hcy)、神經(jīng)元特異性烯醇化酶(NSE)。結(jié)果治療前觀察組和對(duì)照組AIP分別為0.28±0.17、0.28±0.20,治療后觀察組和對(duì)照組AIP分別為0.18±0.14、0.20±0.17,觀察組、對(duì)照組治療后與治療前相比,P0.05,治療后觀察組與對(duì)照組比較,P0.05。治療前觀察組和對(duì)照組NIHSS評(píng)分分別為(24.32±5.41)、(25.04±6.04)分,治療后觀察組和對(duì)照組NIHSS評(píng)分分別為(14.43±4.72)、(17.70±5.69)分,觀察組、對(duì)照組治療后與治療前相比,P0.05,治療后觀察組與對(duì)照組比較,P0.05。與治療前比較,觀察組和對(duì)照組血清IL-10、Hcy、NSE均降低,P均0.05;與對(duì)照組比較,治療后觀察組血清IL-10、Hcy、NSE及NIHSS評(píng)分降低更明顯,P均0.05。結(jié)論華佗再造丸輔助治療急性腦梗死有助于改善患者動(dòng)脈硬化及神經(jīng)功能缺損程度,可降低患者血清IL-10、Hcy、NSE水平。
[Abstract]:Objective to observe the clinical efficacy of Huatuo Zaizhao Pill in the treatment of acute cerebral infarction. Methods 85 patients with acute cerebral infarction were divided into two groups: observation group (n = 43) and control group (n = 42). The two groups were treated with routine clinical cerebral infarction therapy. The observation group was treated with Huatuo Zao Pill (8 g / time, 3 times / d) for 1 month. The arterial sclerosis index (AIP) and the degree of nerve function defect (NIHSS score) were compared between the two groups before and after treatment. The levels of serum interleukin 10 (IL-10) and high homocysteine (Hcy), were measured before and after treatment between the two groups. Neuron specific enolase (NSE). Results before and after treatment, the AIP of observation group and control group were 0.28 鹵0.17,0.28 鹵0.20 respectively. After treatment, the AIP of observation group and control group were 0.18 鹵0.14,0.20 鹵0.17, respectively. The AIP of observation group and control group after treatment were 0.28 鹵0.17,0.28 鹵0.20, P 0.05, respectively. After treatment, the observation group was compared with the control group, P 0.05. The NIHSS scores were (24.32 鹵5.41), (25.04 鹵6.04 in the observation group and (14.43 鹵4.72), (17.70 鹵5.69) in the control group before treatment and (14.43 鹵4.72), (17.70 鹵5.69) in the control group after treatment, respectively. After treatment, P 0.05 in the control group, P 0.05 in the observation group after treatment and P 0.05 in the control group after treatment. Compared with pre-treatment, the serum IL-10,Hcy,NSE in the observation group and the control group decreased significantly (P < 0.05), and the IL-10,Hcy,NSE and NIHSS scores in the observation group decreased more significantly after the treatment than those in the control group (P 0.05). Conclusion Hua Tuo Zao Pill is helpful to improve the degree of arteriosclerosis and nerve function defect in patients with acute cerebral infarction, and can reduce the level of serum IL-10,Hcy,NSE in patients with acute cerebral infarction.
【作者單位】： 南京醫(yī)科大學(xué)附屬腦科醫(yī)院;南京中醫(yī)藥大學(xué);
【分類號(hào)】：R743.3

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