【摘要】：研究目的：應(yīng)用自動功能成像技術(shù)（AFI）定量分析AMI患者左室縱向應(yīng)變，分析其與冠狀動脈造影的相關(guān)性，探討AFI對診斷急性心肌梗死的應(yīng)用價值。 研究方法：在入院48小時內(nèi)分別對AMI患者和對照受檢者各30例行超聲心動圖檢查，記錄連續(xù)3個心動周期的左室心尖長軸、心尖四腔和心尖兩腔二維灰階動態(tài)圖像以及左室心尖五腔觀的主動脈血流頻譜靜態(tài)圖像。應(yīng)用AFI技術(shù)實時獲取左室縱向峰值應(yīng)變（LPSS）牛眼圖及左室整體應(yīng)變平均值，并進行重復(fù)性檢測。記錄AMI患者入院后的冠狀動脈造影結(jié)果，比較AFI與冠狀動脈造影的一致性。 結(jié)果:與對照組相比，心肌梗死組左室各節(jié)段LPSS和左室整體應(yīng)變平均值均明顯減低(P0.001)，牛眼圖的顏色不完全一致。左室整體應(yīng)變平均值與冠狀動脈狹窄率呈正相關(guān)（r=0.56，P0.05）。 AFI測量的左室LPSS有較高的可重復(fù)性。 結(jié)論：AFI可以發(fā)現(xiàn)心肌梗死的發(fā)生，并對其室壁運動進行量化分析。左室整體應(yīng)變平均值可以反映心肌梗死的嚴重程度。AFI的技術(shù)穩(wěn)定，可靠性高；操作人為誤差小，測量值可信度高。AFI作為一種簡便易行的二維斑點追蹤技術(shù)，可以診斷和評價AMI，有廣泛的臨床應(yīng)用價值。
[Abstract]:Objective: to analyze the relationship between left ventricular longitudinal strain and coronary angiography (CAG) by automatic functional imaging (AFI) in patients with AMI, and to explore the value of AFI in the diagnosis of acute myocardial infarction (AMI). Methods: echocardiography was performed in 30 AMI patients and 30 control subjects within 48 hours of admission. The left ventricular apical long axis was recorded in 3 consecutive cardiac cycles. Two dimensional gray-scale dynamic images of apical and apical four lumens and five lumen view of left ventricular apex were obtained. The longitudinal peak strain of left ventricle (LPSS) and the mean value of global strain of left ventricle were obtained by AFI technique in real time. The results of coronary angiography of AMI patients after admission were recorded and the consistency between AFI and coronary angiography was compared. Results: compared with the control group, the mean values of LPSS and global strain of left ventricle in myocardial infarction group were significantly lower than those in control group (P0. 001), and the color of bovine ophthalmogram was not completely consistent. The mean global strain of left ventricle was positively correlated with the rate of coronary artery stenosis (r = 0.56, P 0.05). Left ventricular LPSS measured by AFI has high reproducibility. Conclusion: AFI can detect myocardial infarction and analyze its wall motion quantitatively. The mean global strain of left ventricle can reflect the severity of myocardial infarction. The technique of AFI is stable and reliable. As a simple two-dimensional speckle tracing technique, AFI can be used to diagnose and evaluate AMI,.
【學(xué)位授予單位】：山西醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2013
【分類號】：R445.2;R542.22

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