【摘要】：目的探討右美托咪定應(yīng)用于重癥醫(yī)學(xué)科(ICU)重癥患者床旁纖維支氣管鏡檢查中的鎮(zhèn)靜效果。方法觀察2012年3月至2014年12月在該院ICU病房接受有創(chuàng)機(jī)械通氣治療并需要進(jìn)行纖維支氣管鏡檢查的患者32例,操作過程中給予右美托咪定鎮(zhèn)靜,觀察其鎮(zhèn)靜效果及不良事件的發(fā)生率。結(jié)果患者均在右美托咪定負(fù)荷劑量期間達(dá)到目標(biāo)鎮(zhèn)靜評(píng)分,時(shí)間(8.2±2.1)min;25例患者在纖維支氣管鏡操作期間出現(xiàn)躁動(dòng)鎮(zhèn)靜評(píng)分量表(RASS)評(píng)分≥-3;觀察期間出現(xiàn)不良事件的發(fā)生率為87.5%,其中主要為嗆咳、氣管痙攣,血氧飽和度(Sp O2)下降;操作醫(yī)生對(duì)患者纖維支氣管鏡期間的鎮(zhèn)靜滿意度評(píng)分為(5.8±1.9)分。結(jié)論 ICU重癥患者床旁纖維支氣管鏡檢查中給予右美托咪定鎮(zhèn)靜治療,可部分抑制纖維支氣管鏡操作所引起的應(yīng)激反應(yīng),但難以維持深度鎮(zhèn)靜水平。
[Abstract]:Objective to investigate the sedation effect of dexmetomidine on bedside fiberoptic bronchoscopy in severe (ICU) patients. Methods from March 2012 to December 2014, 32 patients who received invasive mechanical ventilation in ICU ward and needed fiberoptic bronchoscopy were treated with dexmetomidine sedation. The sedation effect and the incidence of adverse events were observed. Results all the patients achieved the goal sedative score during the loading dose of dexmetidine, and the time was (8.2 鹵2.1) min;25 patients developed restlessness sedative score scale (RASS) 鈮，

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