【摘要】：目的:觀察膿毒癥患者血小板計數(shù)(PC)、血小板平均體積(MPV)、血小板分布寬度(PDW)、大血小板比率(P-LCR)的變化,探討血小板參數(shù)在膿毒癥中的臨床意義。方法:94例膿毒癥患者,根據(jù)預(yù)后,回顧性分為死亡組(23例)和存活組(71例),入院當(dāng)天檢測血常規(guī),進行APACHEⅡ評分。根據(jù)APACHEⅡ評分分為A組(10分,12例)、B組(10～19分,39例)和C組(≥20分,43例),分析3組間血小板計數(shù)及病死率。結(jié)果:生存組患者的血小板計數(shù)高于死亡組,而APACHEⅡ評分低于死亡組(均P0.01)。APACHEⅡ評分越高,血小板計數(shù)越低,病死率越高(P0.01)。分析表明血小板參數(shù)與血小板計數(shù)呈負相關(guān)。結(jié)論:血小板減少及其減少程度可作為膿毒癥病情嚴重程度及預(yù)后的早期預(yù)警指標(biāo),血小板相關(guān)參數(shù)MPV、PDW、P-LCR的變化可能間接反應(yīng)骨髓代償增生能力,對膿毒癥血小板減少患者血小板計數(shù)的恢復(fù)存在一定的預(yù)示作用。
[Abstract]:Objective: to observe the changes of platelet count (PC), platelet mean volume (MPV), platelet distribution width (PDW), large platelet ratio (P-LCR) in patients with sepsis and to explore the clinical significance of platelet parameters in sepsis. Methods: 94 patients with sepsis were retrospectively divided into death group (23 cases) and survival group (71 cases) according to their prognosis. Blood routine examination and APACHE 鈪，

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