【摘要】：探討血漿BNP在不同類型老年心力衰竭(簡(jiǎn)稱心衰)患者中,用以預(yù)測(cè)急性失代償心衰(ADHF)的價(jià)值。將80例心衰患者根據(jù)心臟超聲結(jié)果分為左室射血分?jǐn)?shù)降低的心衰(HFrEF)組25例和左室射血分?jǐn)?shù)正常的心衰(HFpEF)組55例,測(cè)定初始血漿BNP值。隨訪1年,記錄ADHF的發(fā)生并再次測(cè)定血漿BNP水平。HFpEF組年齡和BMI更高、初始BNP值更低、心絞痛病史更少、NYHAⅠ級(jí)占比更大(P0.05)。HFpEF組和HFrEF組的ADHF發(fā)生率分別為32.0%和32.7%。HFpEF患者以BNP升高122pg/ml為臨界值,預(yù)測(cè)ADHF敏感度為84.8%、特異度為82.6%;HFrEF患者以BNP升高145pg/ml為臨界值,預(yù)測(cè)ADHF敏感度為93.4%、特異度為47.9%。心衰患者失代償前BNP升高,BNP升高可作為預(yù)測(cè)ADHF的指標(biāo)之一。
[Abstract]:To investigate the value of plasma BNP in predicting acute decompensated heart failure (ADHF) in different types of elderly patients with heart failure. According to the results of echocardiography, 80 patients with CHF were divided into two groups: (HFrEF) group (25 cases) and (HFpEF) group (55 cases) with normal left ventricular ejection fraction (LVEF). The initial plasma BNP level was measured. After one year follow-up, the occurrence of ADHF was recorded and the plasma BNP level was determined again. The age and BMI of HFPEF group were higher, and the initial BNP value was lower. The incidence of ADHF was 32.0% in HFPEF group and 32.0% in HFrEF group. The critical value for predicting ADHF sensitivity was 84.8%, and the specificity was 82.6% for HFrEF patients, and BNP increased 145pg/ml was the critical value for 32.7%.HFpEF patients. The sensitivity and specificity of ADHF prediction were 93. 4 and 47. 9 respectively. The increase of BNP before decompensation may be used as a predictor of ADHF in patients with heart failure.
【作者單位】： 武警湖北省總隊(duì)醫(yī)院心內(nèi)科;
【分類號(hào)】：R541.6

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