【摘要】：目的觀察小劑量糖皮質激素治療感染性休克的臨床療效,并探討其對患者血清感染標志物水平的影響程度,為感染性休克的治療提供參考依據。方法選取2012年2月-2015年9月醫(yī)院收治的60例感染性休克患者為研究對象,將其隨機分為對照組和觀察組,各30例,對照組患者采用常規(guī)治療,觀察組患者在此基礎上加用小劑量糖皮質激素,對比分析兩組患者的血乳酸清除率、APACHEⅡ評分、呼吸機使用時間、病死率、治療前后的血清感染標志物水平。結果觀察組的血乳酸清除率、APACHEⅡ評分、呼吸機使用時間及病死率分別為46.67%、(12.25±1.28)分、(11.67±1.20)d及10.00%,均好于對照組的66.67%、(15.95±1.37)分、(18.25±1.45)d及26.67%,治療后12、24、48h觀察組的血清感染標志物水平也均好于對照組,差異均有統計學意義(P0.05)。結論小劑量糖皮質激素治療感染性休克的臨床療效較好,且對于患者的血清感染標志物水平也有積極的改善作用。
[Abstract]:Objective to observe the clinical efficacy of low dose glucocorticoid in the treatment of septic shock, and to explore the effect of low dose glucocorticoid on serum infection markers in order to provide reference for the treatment of septic shock. Methods from February 2012 to September 2015, 60 patients with septic shock were randomly divided into two groups: control group (n = 30) and observation group (n = 30). Patients in the observation group were treated with low dose glucocorticoid. The serum lactate clearance rate (APACHE 鈪，

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