發(fā)布時(shí)間：2018-08-14 17:36

【摘要】：目的觀察小劑量糖皮質(zhì)激素治療感染性休克的臨床療效,并探討其對(duì)患者血清感染標(biāo)志物水平的影響程度,為感染性休克的治療提供參考依據(jù)。方法選取2012年2月-2015年9月醫(yī)院收治的60例感染性休克患者為研究對(duì)象,將其隨機(jī)分為對(duì)照組和觀察組,各30例,對(duì)照組患者采用常規(guī)治療,觀察組患者在此基礎(chǔ)上加用小劑量糖皮質(zhì)激素,對(duì)比分析兩組患者的血乳酸清除率、APACHEⅡ評(píng)分、呼吸機(jī)使用時(shí)間、病死率、治療前后的血清感染標(biāo)志物水平。結(jié)果觀察組的血乳酸清除率、APACHEⅡ評(píng)分、呼吸機(jī)使用時(shí)間及病死率分別為46.67%、(12.25±1.28)分、(11.67±1.20)d及10.00%,均好于對(duì)照組的66.67%、(15.95±1.37)分、(18.25±1.45)d及26.67%,治療后12、24、48h觀察組的血清感染標(biāo)志物水平也均好于對(duì)照組,差異均有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論小劑量糖皮質(zhì)激素治療感染性休克的臨床療效較好,且對(duì)于患者的血清感染標(biāo)志物水平也有積極的改善作用。
[Abstract]:Objective to observe the clinical efficacy of low dose glucocorticoid in the treatment of septic shock, and to explore the effect of low dose glucocorticoid on serum infection markers in order to provide reference for the treatment of septic shock. Methods from February 2012 to September 2015, 60 patients with septic shock were randomly divided into two groups: control group (n = 30) and observation group (n = 30). Patients in the observation group were treated with low dose glucocorticoid. The serum lactate clearance rate (APACHE 鈪，

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