重癥監(jiān)護(hù)病房撤機(jī)困難患者短期預(yù)后及相關(guān)因素分析
發(fā)布時(shí)間:2018-06-29 02:46
本文選題:機(jī)械通氣 + 撤機(jī); 參考:《廣東醫(yī)學(xué)》2016年19期
【摘要】:目的探討重癥監(jiān)護(hù)病房(ICU)撤機(jī)困難患者相關(guān)危險(xiǎn)因素及短期預(yù)后。方法回顧性分析ICU收治有創(chuàng)機(jī)械通氣82例患者的臨床資料,根據(jù)撤機(jī)情況分為撤機(jī)成功組和撤機(jī)困難組,采用單因素分析篩查出相關(guān)變量進(jìn)行多因素logistic回歸分析,判斷各因素對(duì)撤機(jī)困難的影響。結(jié)果單因素分析顯示,兩組患者平均年齡、體質(zhì)指數(shù)、28 d內(nèi)死亡例數(shù)、神經(jīng)肌肉疾病、惡性腫瘤、重癥急性胰腺炎、腎功能不全、心功能不全、精神心理疾病比較差異有統(tǒng)計(jì)學(xué)意義(P0.05)。撤機(jī)前24 h內(nèi)生理生化指標(biāo)血清前白蛋白、血肌酐、氧合指數(shù)、APACHEⅡ評(píng)分比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。多因素分析結(jié)果顯示年齡、前白蛋白、APACHEⅡ評(píng)分、心功能不全進(jìn)入回歸模型(P0.05),是ICU撤機(jī)困難患者的影響因素。結(jié)論對(duì)患者的綜合評(píng)估是順利撤機(jī)的關(guān)鍵,臨床醫(yī)師的經(jīng)驗(yàn)也起到重要作用。
[Abstract]:Objective to investigate the risk factors and short-term prognosis of patients with difficult weaning in intensive care unit (ICU). Methods the clinical data of 82 patients with invasive mechanical ventilation were analyzed retrospectively. According to the condition of weaning, the patients were divided into successful weaning group and difficult weaning group. Single factor analysis was used to screen the related variables for multivariate logistic regression analysis. To judge the influence of various factors on the difficulty of machine withdrawal. Results univariate analysis showed that the average age, body mass index (BMI) and death rate within 28 days, neuromuscular disease, malignant tumor, severe acute pancreatitis, renal insufficiency, cardiac insufficiency, and so on. The difference of psychosomatic disease was statistically significant (P0.05). The scores of serum prealbumin, serum creatinine, oxygenation index and Apache 鈪,
本文編號(hào):2080490
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