本文選題：感染性休克 + 早期集束化治療��； 參考：《廣東醫(yī)學(xué)》2017年18期

【摘要】：目的觀察感染性休克患者采取早期集束化治療的臨床效果。方法將連續(xù)入組的80例感染性休克患者隨機(jī)分為早期集束化治療組(40例)和傳統(tǒng)治療組(40例)。記錄兩組患者入院時(shí)急性生理和慢性健康評分(APACHEⅡ),觀察兩組患者復(fù)蘇終點(diǎn)、器官功能變化、生存時(shí)間、病死率。結(jié)果最初治療6h時(shí),傳統(tǒng)治療組患者平均動脈壓(MAP)明顯低于早期集束化治療組(P0.001);傳統(tǒng)治療組的患者中心靜脈血氧飽和度(Scv O2)、MAP顯著低于早期集束化治療組(P0.001)。治療后72 h時(shí)傳統(tǒng)治療組患者的APACHEⅡ評分及多器官功能衰竭(MODS)明顯高于早期集束化治療組(P0.001)。傳統(tǒng)治療組總的病死率明顯高于早期集束化治療組(P=0.025),兩組生存曲線分析顯示,早期集束化治療組患者平均生存時(shí)間(133.66±26.77)d,95%可信區(qū)間(95%CI)為27.824~58.176;傳統(tǒng)治療組平均生存時(shí)間(31.334±2.376)d,95%CI:24.619~3 1.381;隨時(shí)間的延長,兩組生存率逐漸下降,但傳統(tǒng)治療組患者生存率明顯低于早期集束化治療組。結(jié)論早期集束化治療可以減少感染性休克患者多臟器功能衰竭發(fā)生率,降低病死率。
[Abstract]:Objective to observe the clinical effect of early cluster therapy in patients with septic shock. Methods 80 consecutive septic shock patients were randomly divided into early cluster therapy group (n = 40) and traditional treatment group (n = 40). The acute physiological and chronic health scores of the two groups were recorded. The end point of resuscitation, organ function, survival time and mortality were observed. Results at the beginning of 6 h treatment, the mean arterial pressure (MAPP) in the traditional treatment group was significantly lower than that in the early cluster therapy group (P 0.001), and the central venous oxygen saturation (scvO _ 2) map in the traditional treatment group was significantly lower than that in the early cluster therapy group (P 0.001). At 72 hours after treatment, the scores of APACHE 鈪，

本文編號：1900207