本文選題：重型顱腦外傷　切入點(diǎn)：感染　出處：《中華醫(yī)院感染學(xué)雜志》2016年07期

【摘要】：目的探討神經(jīng)外科重型腦外傷患者術(shù)后感染、病原菌及耐藥性,并分析控制術(shù)后感染的對(duì)策,以減少多重感染。方法選取醫(yī)院2006-2013年重型腦外傷手術(shù)患者219例,對(duì)發(fā)生感染的患者留取標(biāo)本進(jìn)行病原菌培養(yǎng)和鑒定,數(shù)據(jù)采用WHONET 5.4軟件進(jìn)行統(tǒng)計(jì)分析。結(jié)果 2006-2013年重型顱腦外傷手術(shù)患者219例,其中發(fā)生感染69例,感染率31.51%;69例感染患者共培養(yǎng)出257株病原菌,以革蘭陰性菌為主,共195株占75.88%;主要革蘭陰性菌對(duì)亞胺培南和頭孢哌酮/舒巴坦的耐藥率較低,均20.00%。結(jié)論神經(jīng)外科重型腦外傷術(shù)后患者醫(yī)院感染的發(fā)生率較高,多為多藥耐藥菌感染,臨床應(yīng)采取措施控制感染的發(fā)生,發(fā)現(xiàn)患者有感染,應(yīng)立即分離培養(yǎng)病原菌及耐藥試驗(yàn),后給予針對(duì)性治療,避免發(fā)生多重感染。
[Abstract]:Objective to investigate postoperative infection, pathogenic bacteria and drug resistance in patients with severe brain trauma in neurosurgery, and to analyze the countermeasures to control postoperative infection in order to reduce multiple infections. Methods 219 patients with severe brain trauma in hospital from 2006 to 2013 were selected. The pathogens were cultured and identified in the specimens collected from the infected patients. The data were analyzed by WHONET 5.4 software. Results from 2006 to 2013, there were 219 patients with severe craniocerebral trauma, 69 of whom were infected. 257 strains of pathogenic bacteria were cultured in 69 patients with infection rate of 31.51%, among which 195 strains were Gram-negative bacteria (75.88%), and the resistance rate of the main gram-negative bacteria to imipenem and cefoperazone / sulbactam was low, and the rate of resistance to imipenem and cefoperazone / sulbactam was lower. Conclusion the incidence of nosocomial infection in patients with severe brain trauma after neurosurgery is higher, most of them are multidrug resistant bacteria infection. Clinical measures should be taken to control the occurrence of infection. After the targeted treatment, to avoid multiple infections.
【作者單位】： 江山市人民醫(yī)院神經(jīng)外科;江山市人民醫(yī)院呼吸內(nèi)科;江山市人民醫(yī)院院感科;
【基金】：浙江省醫(yī)藥衛(wèi)生科技基金資助項(xiàng)目(2011KYA166)
【分類號(hào)】：R651.15;R197.323
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本文編號(hào)：1655074