血尿素氮對(duì)呼吸危重癥患者預(yù)后評(píng)估的價(jià)值
發(fā)布時(shí)間:2018-02-22 08:23
本文關(guān)鍵詞: RICU 白蛋白 肌酐 尿素 危險(xiǎn)因素 出處:《東南大學(xué)學(xué)報(bào)(醫(yī)學(xué)版)》2017年02期 論文類型:期刊論文
【摘要】:目的:分析并預(yù)測(cè)血尿素氮對(duì)呼吸危重癥患者死亡風(fēng)險(xiǎn)的預(yù)測(cè)價(jià)值,為臨床對(duì)疾病的預(yù)后及轉(zhuǎn)歸的預(yù)測(cè)提供幫助。方法:選擇入住呼吸重癥監(jiān)護(hù)病房(RICU)的患者共373名,根據(jù)患者的預(yù)后分為死亡組及存活組,對(duì)兩組患者進(jìn)行住院時(shí)間、APACHEⅡ評(píng)分及血尿素氮等檢查,分別采用T檢驗(yàn)、Logistic回歸分析及ROC曲線下面積等方法,分析影響RICU患者預(yù)后的相關(guān)因素。結(jié)果:患者存活率為71.05%,死亡率為28.95%。死亡組和存活組APACHEⅡ評(píng)分,入院及出院時(shí)白蛋白、血尿素氮,出院時(shí)肌酐比較,差異均有統(tǒng)計(jì)學(xué)意義(P0.05)。RICU住院時(shí)間、APACHEⅡ評(píng)分及血尿素氮是影響RICU患者預(yù)后的獨(dú)立因素,其中住院時(shí)間的回歸系數(shù)為0.013,優(yōu)勢(shì)比(OR)為1.013,(P0.05);APACHEⅡ評(píng)分的回歸系數(shù)為-0.117,優(yōu)勢(shì)比(OR)為0.890(P0.05);出院尿素回歸系數(shù)為-0.063,優(yōu)勢(shì)比(OR)為0.939(P0.05),以血尿素氮為10.65 mmol·L~(-1)截點(diǎn)分為低危組與高危組,對(duì)預(yù)后的預(yù)測(cè)最佳。結(jié)論:呼吸危重癥患者血尿素氮增加與預(yù)后不良相關(guān),RICU住院時(shí)間、APACHEⅡ評(píng)分及血尿素氮是影響RICU患者預(yù)后的獨(dú)立因素,RICU臨床醫(yī)生可根據(jù)BUN值及變化幅度對(duì)預(yù)后進(jìn)一步評(píng)估。
[Abstract]:Objective: to analyze and predict the value of blood urea nitrogen in predicting the risk of death in respiratory critical patients, and to provide help in predicting the prognosis and outcome of the disease. Methods: 373 patients were selected to be admitted to respiratory intensive care unit (RICU). According to the prognosis of the patients, the patients were divided into two groups: death group and survival group. Apache 鈪,
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