急性腦梗死患者低頻重復(fù)經(jīng)顱磁刺激療效分析
本文關(guān)鍵詞: 低頻重復(fù)經(jīng)顱磁刺激(r TMS) 急性腦梗死 療效 出處:《中國公共衛(wèi)生》2017年07期 論文類型:期刊論文
【摘要】:目的分析低頻重復(fù)經(jīng)顱磁刺激(rTMS)對(duì)急性腦梗死患者的療效,為急性腦梗死的治療提供科學(xué)依據(jù)。方法整群抽取2016年1—11月在河北承德醫(yī)學(xué)院附屬醫(yī)院接受治療的200例急性腦梗死伴有偏癱患者,將其隨機(jī)分為rTMS組和常規(guī)組各100例,2組均給予常規(guī)康復(fù)治療,rTMS組同時(shí)給予rTMS治療,比較2組患者的美國國立衛(wèi)生研究院卒中量表(NIHSS)評(píng)分、巴氏指數(shù)(BI)、Fugl-Meyer評(píng)分、運(yùn)動(dòng)誘發(fā)電位(MEP)潛伏期、MEP波幅、中樞運(yùn)動(dòng)傳導(dǎo)時(shí)間(CMCT)和漢密爾頓焦慮量表(HAMA)評(píng)分等指標(biāo),以評(píng)價(jià)rTMS對(duì)急性腦梗死患者的療效。結(jié)果rTMS組與常規(guī)組患者治療前比較,2組患者NIHSS評(píng)分、BI指數(shù)、Fugl-Meyer評(píng)分、MEP潛伏期、MEP波幅、CMCT、HAMA評(píng)分等指標(biāo)差異均無統(tǒng)計(jì)學(xué)意義(均P0.05);治療2周后,rTMS組患者的BI指數(shù)[(69.43±7.85)%]、Fugl-Meyer評(píng)分[(65.20±6.84)分]和MEP波幅[(1.04±0.19)mv]均高于常規(guī)組患者的[(63.18±8.40)%]、[(60.88±7.47)分]和[(0.91±0.15)mv],NIHSS評(píng)分[(5.13±1.96)分]、MEP潛伏期[(23.72±0.43)ms]和CMCT[(10.11±0.49)ms]均低于常規(guī)組患者的[(5.72±1.88)分]、[(24.10±0.38)ms]和[(10.67±0.43)ms],差異均有統(tǒng)計(jì)學(xué)意義(均P0.05);治療4周后,rTMS組患者的BI指數(shù)[(83.20±8.17)%]、Fugl-Meyer評(píng)分[(74.12±6.65)分]和MEP波幅[(1.15±0.16)mv]均高于常規(guī)組患者的[(76.94±9.35)%]、[(69.36±7.17)分]和[(0.96±0.18)mv],NIHSS評(píng)分[(3.27±1.05)分]、MEP潛伏期[(23.12±0.36)ms]、CMCT[(9.62±0.51)ms]和HAMA評(píng)分[(7.53±1.86)分]均低于常規(guī)組患者的[(4.06±1.13)分]、[(23.70±0.47)ms]、[(10.01±0.64)ms]和[(8.96±1.97)分],差異均有統(tǒng)計(jì)學(xué)意義(均P0.05)。結(jié)論rTMS可明顯改善急性腦梗死患者的運(yùn)動(dòng)功能及焦慮狀態(tài)。
[Abstract]:Objective to analyze the effect of low frequency repetitive transcranial magnetic stimulation (RTMS) on patients with acute cerebral infarction. Methods 200 patients with acute cerebral infarction with hemiplegia were selected from 2016 to November in affiliated Hospital of Chengde Medical College of Hebei Province. They were randomly divided into two groups: rTMS group and routine group (n = 100). Both groups were given routine rehabilitation therapy and rTMS treatment. The NIHSS scores of the two groups were compared, and the Pap index Fugl-Meyer score was compared between the two groups. The latent period of motor evoked potential (MEP), the amplitude of MEP, the central motor conduction time (CMCTs) and the Hamilton anxiety scale (Hama) score, etc. Results there was no significant difference in NIHSS score and Fugl-Meyer score between rTMS group and routine group before treatment, and there was no significant difference in NIHSS latency and amplitude of MEP wave and Hama score between rTMS group and control group (P 0.05). The BI index [69.43 鹵7.85mv] Fugl-Meyer score [65.20 鹵6.84] and the amplitude of MEP (1.04 鹵0.19mv) in the rTMS group were significantly higher than those in the normal group [63.18 鹵8.40%], [60.88 鹵7.47] and [0.91 鹵0.15mv] [5.13 鹵1.96] and the latency of MEP [23.72 鹵0.43ms] and CMCT [10.11 鹵0.491ms] were significantly lower than those in the normal group [63.18 鹵8.40%] and [0.91 鹵0.15mv] [5.13 鹵1.96], respectively. There was significant difference in the latency of MEP [23.72 鹵0.43 Ms] and CMCT [10.11 鹵0.49 Ms]. The BI index [83.20 鹵8.17g%] Fugl-Meyer score [74.12 鹵6.65] and the MEP amplitude [1.15 鹵0.16mv] in the rTMS group [76.94 鹵9.35%], [69.36 鹵7.17) minutes] and [0.96 鹵0.18mv] NIHSS score [3.27 鹵1.05m] in the control group were significantly lower than those in the routine group [23.12 鹵0.36ms] and HAMA scores [9.62 鹵0.51ms] and 0.64ms 鹵0.64ms (7.53 鹵1.86mv). [0.96 鹵0.18mv] [3.27 鹵1.05mV] [23.12 鹵0.36ms] and HAMA scores [7.53 鹵1.86ms] were significantly lower than those in the routine group [76.94 鹵9.35mv] and [0.96 鹵0.18mv] [3.27 鹵1.05m] and [23.12 鹵0.36ms] and HAMA scores (7.53 鹵1.86ms), respectively. The difference was statistically significant (P 0.05). Conclusion rTMS can significantly improve motor function and anxiety state in patients with acute cerebral infarction.
【作者單位】: 承德醫(yī)學(xué)院附屬醫(yī)院老年病科;
【分類號(hào)】:R743.33
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