發(fā)布時(shí)間：2018-02-09 05:47

  本文關(guān)鍵詞： 腦梗死 D二聚體 左室射血分?jǐn)?shù) NIHSS評(píng)分　出處：《山東醫(yī)藥》2016年15期 　論文類型：期刊論文

【摘要】：目的觀察不用梗死部位急性腦梗死患者血漿D二聚體水平變化,并分析其與神經(jīng)功能缺損程度的關(guān)系。方法急性腦梗死患者150例,其中梗死部位位于小腦、腦干、基底節(jié)、大腦皮層、多部位者各30例(分別計(jì)為小腦組、腦干組、基底節(jié)組、大腦皮層組、多部位組),比較各組血漿D二聚體水平、左室射血分?jǐn)?shù)(LVEF)及入院第1、10天NIHSS評(píng)分。結(jié)果與多部位組比較,其余4組血漿D二聚體水平降低;與小腦組及基底節(jié)組比較,腦干組、大腦皮層組血漿D二聚體水平升高;與大腦皮層組比較,其余4組LVEF增加;P均0.05。與小腦組比較,其余4組入院第1、10天NIHSS評(píng)分增加,神經(jīng)功能缺損改善程度明顯;與多部位組比較,其余4組入院第1、10天NIHSS評(píng)分降低;與大腦皮層組比較,腦干組入院第1天NIHSS評(píng)分增加,神經(jīng)功能缺損改善程度明顯;P均0.05。Spearman相關(guān)分析顯示,D二聚體水平與入院第1、10天NIHSS評(píng)分呈正相關(guān)(r分別為0.395、0.414,P均0.05)。結(jié)論不同梗死部位急性腦梗死患者血漿D二聚體水平不同,其與神經(jīng)功能缺損程度相關(guān);此指標(biāo)可作為病情及病變部位診斷的參考依據(jù),亦可作為患者神經(jīng)功能預(yù)后的參考指標(biāo)。
[Abstract]:Objective to observe the changes of plasma D-dimer level in patients with acute cerebral infarction without infarction, and to analyze the relationship between D-dimer and the degree of neurological deficit. Methods 150 patients with acute cerebral infarction were treated with acute cerebral infarction, including cerebellum, brainstem, basal ganglia. There were 30 cases of cerebral cortex and 30 cases of multiple sites (cerebellar group, brainstem group, basal ganglia group, cerebral cortex group, multisite group). Left ventricular ejection fraction (LVEF) and NIHSS score on the 1st day after admission. Results compared with the multisite group, the plasma D-dimer levels in the other 4 groups were lower, and those in the brainstem group and cerebral cortex group were higher than those in the cerebellar group and basal ganglia group. Compared with the cerebral cortex group, the other four groups increased LVEF (P 0.05). Compared with the cerebellar group, the NIHSS score of the other four groups increased on the 1st day after admission, and the nerve function defect improved significantly, and the NIHSS score of the other four groups decreased on the 1st day after admission compared with the multi-site group. Compared with the cerebral cortex group, the NIHSS score of the brainstem group increased on the first day of admission. The degree of improvement of neurological function defect was significantly improved (P < 0.05). Spearman correlation analysis showed that there was a positive correlation between D dimer level and NIHSS score on the 1st day of admission, respectively. Conclusion the plasma D dimer levels are different in patients with acute cerebral infarction at different infarct sites. This index can be used as a reference for the diagnosis of the disease and the location of the lesion, as well as as a reference index for the prognosis of the neurological function of the patients.
【作者單位】： 天津醫(yī)科大學(xué)總醫(yī)院;
【分類號(hào)】：R743.33

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本文編號(hào)：1497219