發(fā)布時(shí)間：2018-02-03 01:18

  本文關(guān)鍵詞： 膿毒血癥 乳酸清除率 腦利鈉肽 APACHEⅡ評(píng)分　出處：《中華醫(yī)院感染學(xué)雜志》2016年23期 　論文類型：期刊論文

【摘要】：目的探討乳酸清除率(LCR)與腦利鈉肽(BNP)的動(dòng)態(tài)變化評(píng)估肝膽外科患者膿毒血癥預(yù)后的臨床意義,為治療提供參考依據(jù)。方法選取2012年6月-2015年6月醫(yī)院肝膽外科ICU確診為膿毒血癥患者64例,根據(jù)診斷膿毒血癥后28天的生存狀況分為死亡組43例和存活組21例;分析兩組患者第1、3、5天LCR、BNP和急性生理與APACHEⅡ評(píng)分的動(dòng)態(tài)變化,評(píng)估LCR及BNP對(duì)患者預(yù)后評(píng)估的臨床意義。結(jié)果與生存組患者相比,死亡組患者在診斷膿毒血癥后第1天LCR、BNP及APACHEⅡ評(píng)分差異均無(wú)統(tǒng)計(jì)學(xué)意義;第3、5天LCR、BNP差異及第5天APACHEⅡ評(píng)分差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論肝膽外科膿毒血癥患者LCR及BNP的動(dòng)態(tài)變化與病情密切相關(guān),與APACHEⅡ評(píng)分聯(lián)合對(duì)患者的預(yù)后具有臨床指導(dǎo)意義。
[Abstract]:Objective to investigate the clinical significance of dynamic changes of lactate clearance rate (LCR) and brain natriuretic peptide (BNP) in evaluating the prognosis of sepsis in patients with hepatobiliary surgery. Methods 64 patients with sepsis diagnosed by ICU from June 2012 to June 2015 were selected. According to the survival status of 28 days after diagnosis of sepsis, 43 patients were divided into death group (43 cases) and survival group (21 cases). The dynamic changes of LCR-BNP, acute physiology and APACHE 鈪，

本文編號(hào)：1485997