【摘要】：目的了解河北省2009-2015年流感病原學特征,為流感防控提供科學依據(jù)。方法采用描述性流行病學方法對2009年4月1日-2015年3月31日的流感病原學監(jiān)測資料進行分析。結果采集的63 397份流感樣病例(Influenza-like Illness,ILI)標本經(jīng)流感病毒核酸檢測,10 705份陽性(陽性率為16.89%),其中甲型H1N1亞型4 179份,季節(jié)性H3亞型3 674份,B型2 595份,A型未分型230份,季節(jié)性H1亞型10份,混合型15份。傳代狗腎細胞分離到流感毒株2 865株。6個監(jiān)測年度流感病毒核酸陽性率分別為29.18%、12.58%、12.97%、13.34%、11.64%和15.95%,2009-2010年度流感病毒核酸檢測陽性率顯著高于其余5個監(jiān)測年度(χ2=1997.585,P0.01);6個監(jiān)測年度,流感流行的高峰期分別為11月、1月、2月、1月、1月、12月,優(yōu)勢病毒分別為甲型H1N1流感、甲型H1N1+季節(jié)性H3流感、B型流感、季節(jié)性H3+甲型H1N1流感、甲型H1N1流感、季節(jié)性H3流感;2013年之前,B-Victoria系為主要流行型別,自2012年B-Yamagata系出現(xiàn)后取代B-Victoria系成為主要的流行株;0~、5~、15~、25~和≥60歲年齡組的陽性率分別為12.12%、24.88%、18.25%、15.99%和13.78%,陽性率差異有統(tǒng)計學意義(χ2=880.864,P0.01),5~歲年齡組陽性率最高。結論 2009-2015年河北省以甲型H1N1流感病毒流行為主;隨年度甲型H1N1、季節(jié)性H3、B型流感病毒呈共同或先后交替流行的特點;高峰期出現(xiàn)在當年11月~次年2月,5~年齡組為易感人群。
[Abstract]:Objective to understand the etiological characteristics of influenza in Hebei Province from 2009 to 2015, and to provide scientific basis for influenza prevention and control. Methods descriptive epidemiological method was used to analyze the etiological surveillance data of influenza from April 1, 2009 to March 31, 2015. Results 63 397 influenza like cases (Influenza-like Illness,ILI) were detected by influenza virus nucleic acid, and 10 705 samples were positive (the positive rate was 16.89%). Among them, 4 179 were type A H1N1, 3 674 were seasonal H3, 2 595 were type B, 4 179 were influenza A subtypes, 3 674 were seasonal H3 subtypes, 2 595 were influenza B, 10 705 were positive (positive rate was 16.89%). There were 230 unclassified type A, 10 seasonal H 1 subtypes and 15 mixed types. 2865 strains of influenza virus were isolated from subculture dog kidney cells. The positive rates of nucleic acid of influenza virus in six monitoring years were 29.18%, 12.58%, 12.97%, 13.34%, 11.64% and 15.95%, respectively. The positive rate of influenza virus nucleic acid detection in 2009 / 2010 was significantly higher than that in the other five monitoring years (蠂 ~ 2 鈮，

本文編號：2487414