【摘要】：目的總結(jié)泛耐藥鮑氏不動桿菌(PDRAB)醫(yī)院感染患者的臨床特點,分析其感染患者的預(yù)后危險因素,為臨床治療提供合理依據(jù)。方法回顧性總結(jié)2010年1月-2012年12月176例PDRAB醫(yī)院感染患者臨床資料,根據(jù)其預(yù)后分為存活組110例和死亡組66例,采用單因素分析及l(fā)ogistic逐步回歸法對感染患者的危險因素進行分析。結(jié)果 176例PDRAB醫(yī)院感染患者死亡66例,病死率為37.5%;多發(fā)生于中心ICU占60.8%,其次為燒傷病區(qū)占22.7%;主要為下呼吸道感染占80.7%,其次為創(chuàng)面分泌物占10.9%,血液、靜脈導(dǎo)管、泌尿道感染分別占4.5%、2.8%、1.1%;存活組與死亡組比較,年齡、基礎(chǔ)疾病、機械通氣、惡性腫瘤、總住院時間、ICU治療時間和APACHEⅡ評分等7個危險因素,差異均有統(tǒng)計學(xué)意義(P0.05);多因素logistic回歸分析后發(fā)現(xiàn)APACHEⅡ評分(P=0.000,OR值1.414,95%CI 1.262~1.585)是死亡的獨立危險因素(P0.01)。結(jié)論 PDRAB醫(yī)院感染患者病死率較高,高齡、基礎(chǔ)疾病多、ICU住院時間長等多種危險因素對患者的預(yù)后產(chǎn)生不良影響,APACHEⅡ評分是PDRAB感染患者預(yù)后危險因素的重要評估指標(biāo)。
[Abstract]:Objective to summarize the clinical characteristics and prognostic risk factors of patients with nosocomial infection of pan-drug resistant Acinetobacter baumannii (PDRAB), so as to provide a reasonable basis for clinical treatment. Methods the clinical data of 176 patients with PDRAB nosocomial infection from January 2010 to December 2012 were retrospectively reviewed. According to their prognosis, they were divided into survival group (110 cases) and death group (66 cases). Univariate analysis and logistic stepwise regression were used to analyze the risk factors of infected patients. Results 66 cases died of PDRAB nosocomial infection, the mortality rate was 37.5%, most of them occurred in the center of ICU (60.8%), followed by burn area (22.7%), the mortality rate was 37.5%, and the mortality rate was 37.5%. The main causes were lower respiratory tract infection (80.7%), wound secretion (10.9%), blood infection (4.5%), venous catheter (2.8%) and urinary tract infection (1.1%). There were significant differences in age, basic disease, mechanical ventilation, malignant tumor, total hospital stay, ICU treatment time and Apache 鈪，

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