【摘要】：目的分析5例埃博拉病毒病(Ebola virus disease,EVD)確診患者的診治情況,為更好地防治EVD提供科學(xué)依據(jù)。方法 2014年12月5日至2015年1月17日在利比里亞中國埃博拉治療中心(Ebola Treatment Center,ETC)收治5例EVD確診患者,對(duì)其流行病學(xué)資料、癥狀、體征、實(shí)驗(yàn)室檢查及治療轉(zhuǎn)歸情況進(jìn)行分析。結(jié)果本次確診的5例患者,其中3例為家庭聚集性發(fā)病;有3例患者首次埃博拉病毒核酸檢測為陰性,第2次復(fù)檢為陽性;臨床表現(xiàn)以發(fā)熱、乏力、嘔吐、腹瀉等為主,少有出血相關(guān)癥狀及體征;通過盡早采取退熱、補(bǔ)液等對(duì)癥、支持治療,3例患者康復(fù)出院,2例死亡。結(jié)論對(duì)有明確密切接觸史但首次埃博拉核酸檢測陰性的患者,必須于72 h后復(fù)檢;治療上目前仍以對(duì)癥支持治療為主,治療的重點(diǎn)是糾正水、電解質(zhì)紊亂,維持內(nèi)環(huán)境穩(wěn)定,預(yù)防并發(fā)癥的發(fā)生。
[Abstract]:Objective to analyze the diagnosis and treatment of 5 patients with Ebola virus disease (Ebola virus disease,EVD) and to provide scientific basis for better prevention and treatment of EVD. Methods from December 5, 2014 to January 17, 2015, five patients with EVD were treated in (Ebola Treatment Center,ETC, China Ebola treatment Center in Liberia. The epidemiological data, symptoms and signs were analyzed. Laboratory examination and treatment outcome were analyzed. Results among the 5 confirmed cases, 3 cases were familial agglomeration, 3 cases were negative for Ebola virus nucleic acid for the first time and the second time was positive for Ebola virus nucleic acid, and 3 cases were positive for Ebola virus nucleic acid for the first time. The clinical manifestations were fever, fatigue, vomiting, diarrhea, etc. There were few symptoms and signs associated with hemorrhage, and 3 patients recovered and 2 died after treatment with antipyrexia and fluid rehydration as soon as possible. Conclusion for patients with a clear history of close contact but negative detection of Ebola nucleic acid for the first time, they must be re-examined 72 hours later. At present, the treatment is based on symptomatic support therapy. The focus of treatment is to correct the disturbance of water and electrolyte, to maintain the stability of internal environment and to prevent the occurrence of complications.
【作者單位】： 中國人民解放軍首批援利醫(yī)療隊(duì);第三軍醫(yī)大學(xué)西南醫(yī)院;第三軍醫(yī)大學(xué)新橋醫(yī)院;
【分類號(hào)】：R512.8

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