本文選題：妊娠合并梅毒　切入點：妊娠結(jié)局　出處：《南京醫(yī)科大學學報(自然科學版)》2015年11期 　論文類型：期刊論文

【摘要】：目的:探討孕母梅毒快速血漿反應試驗(rapid plasma regain,RPR)滴度與新生兒RPR陽性率及圍生結(jié)局關(guān)系。方法:對2009年1月1日—2014年2月1日經(jīng)RPR和梅毒螺旋體顆粒凝集試驗篩查,192例妊娠合并梅毒孕母分娩前及其部分新生兒出生時及6月齡時外周血檢測,比較孕母RPR滴度與新生兒RPR陽性率、陰轉(zhuǎn)率及不良圍生結(jié)局的關(guān)系。結(jié)果:新生兒RPR滴度與孕母呈正相關(guān),孕母RPR滴度1∶1時,新生兒RPR陽性率68.4%;孕母RPR滴度1∶2時,新生兒RPR陽性率87.0%;當孕母RPR滴度≥1∶8時,新生兒RPR陽性率100.0%;孕母RPR滴度≥1∶8與≤1∶4比較,新生兒RPR陽性率差異有統(tǒng)計學意義(P0.05)。孕母RPR滴度≥1∶8時,嬰兒6月齡RPR陰轉(zhuǎn)率下降,與RPR滴度≤1∶4比較,差異有統(tǒng)計學意義(P0.05)。隨著孕母RPR滴度的升高,畸形、死胎及新生兒死亡、早產(chǎn)及先天性梅毒的風險升高,嬰兒不良結(jié)局風險升高。當孕母RPR滴度≥1∶8時,與孕母RPR滴度≤1∶4比較,新生兒畸形、早產(chǎn)、先天性梅毒增多,差異有統(tǒng)計學意義(P0.05)。結(jié)論:隨著孕母RPR滴度的升高,新生兒RPR陽性率升高,當RPR滴度≥1∶8時,新生兒RPR陽性率為100%,6月齡陰轉(zhuǎn)率下降,胎兒畸形、早產(chǎn)、先天性梅毒發(fā)生率顯著升高。
[Abstract]:Objective: to investigate the relationship between the titer of rapid plasma response test (RPR) and neonatal RPR positive rate and perinatal outcome. Methods: RPR and Treponema pallidum particle agglutination test were performed from January 1st 2009 to February 2014 to screen the pregnant women with syphilis Treponema pallidum granulocyte agglutination test. Peripheral blood was detected in 192 pregnant women with syphilis before delivery and at birth of some newborns and at the age of 6 months. Results: there was a positive correlation between neonatal RPR titer and maternal adverse perinatal outcome. Results: at 1: 1 RPR titer of pregnant mother, the positive rate of neonatal RPR was 68.4%, and that of maternal RPR titer was 1: 2. The positive rate of neonatal RPR was 87.0.The positive rate of neonatal RPR was 100.0when the RPR titer of pregnant mother was 鈮，

本文編號：1605766