發(fā)布時(shí)間：2020-12-15 01:11

　　In order to explore the evidence of transient neuronal plasticity observed in human sensorimotor cortex during development of learning, the mechanisms of activity-dependent synaptic modification in cultured cortical sensorimotor neurons in rats were studied. Long-term potentiation （LTP） is an activity-dependent strengthening of synaptic efficacy that is considered to be one of indexes of learning and memory in the present study. Voltage pulse, as a model of repetitive electrical stimulation, was... 

【文章來(lái)源】：中國(guó)人民解放軍軍事科學(xué)院北京市

【文章頁(yè)數(shù)】：75 頁(yè)

【學(xué)位級(jí)別】：博士

【文章目錄】：
Abstract
Introduction
Experimental procedures
    Ⅰ． Cell culture
    Ⅱ． Solutions
    Ⅲ． Electrophysiology
    Ⅳ． Data analysis and statistics
Results
    Ⅰ． Cortical sensorimotor neurons in VLD cultures
    Ⅱ． Voltage-gated ionic channels
    Ⅲ． Spontaneous neuronal activity of cortical sensorimotor neuron
    Ⅳ． Properties of spontaneous EPSCs of cortical sensorimotor neurons
    Ⅴ． Voltage-pulses potentiate spontaneouse neuronal activity
    Ⅵ． NMDA application potentiates synaptic transmission
Discussion
Summary
References
Acknowledgement
Abbreviations
List of publications


【參考文獻(xiàn)】：
期刊論文
[1]乙酰膽堿對(duì)培養(yǎng)大鼠皮層神經(jīng)元興奮性及抑制性突觸電流的相反作用[J]. 劉青松,何湘平,劉傳繢.  生理學(xué)報(bào). 1996(04)



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