【摘要】：目的:通過神經(jīng)介入技術(shù)超選上矢狀竇結(jié)合多功能心電監(jiān)護儀體外壓力測試系統(tǒng),測定上矢狀竇血栓患者及全腦血管造影陰性患者顱內(nèi)靜脈竇的上矢狀竇壓力值,應(yīng)用統(tǒng)計學(xué)軟件計算出上矢狀竇患者靜脈竇壓力與靜脈系統(tǒng)造影陰性患者上矢狀竇壓力的差異,探討上矢狀竇壓力對上矢狀竇血栓患者疾病嚴(yán)重程度的評估以及該病的預(yù)后的影響。方法:收集2015年3月至2016年10月,因靜脈竇血栓就診于河北省人民醫(yī)院并經(jīng)過DSA確診為上矢狀竇血栓并均選擇保守治療的22例患者作為觀察組,男6例,女16例,年齡20~43歲(29.54±6.06)歲。入院時根據(jù)格拉斯哥昏迷評分,將患者分為4組,15分為A組,12-14分為B組,9-11分為C組,3-8分為D組。選取同時間段內(nèi)于我院神經(jīng)外科門診就診的56例因體檢發(fā)現(xiàn)靜脈系統(tǒng)異常,經(jīng)腦血管造影靜脈系統(tǒng)正常表現(xiàn)者作為對照組,男16例,女40例,年齡22~46歲(30.18±5.19)歲,排除顱內(nèi)血管病變、顱內(nèi)高壓、顱腦外傷、顱內(nèi)占位性等病變。應(yīng)用神經(jīng)介入技術(shù)超選上矢狀竇,將微導(dǎo)管頭端置于上矢狀竇血栓遠(yuǎn)端,微導(dǎo)管尾端連接多功能心電監(jiān)護儀體外壓力測試系統(tǒng)測量并記錄上矢狀竇壓力。應(yīng)用統(tǒng)計學(xué)方法分析測量結(jié)果,觀察組與對照組的上矢狀竇壓力與病情嚴(yán)重程度進行相關(guān)性分析。自發(fā)病2個月后,應(yīng)用MBI評分標(biāo)準(zhǔn)評價觀察組患者,與入院時測得的上矢狀竇壓力進行相關(guān)性分析。結(jié)果:測得觀察組4組上矢狀竇的壓力,A組為15.31±0.21cmH2O,B組為18.30±0.25cmH2O,C組為23.75±0.49cmH2O,D組為26.83±0.60cmH2O,對照組的上矢狀竇壓力為14.71±0.09 cmH2O。經(jīng)過SNK-q檢驗,B、C、D組上矢狀竇壓力與觀察組上矢狀竇存在顯著差異,A組上矢狀竇壓力尚不能證實與對照組存在顯著差異。男性和女性在上矢狀竇壓力測定在統(tǒng)計學(xué)上無明顯差異。自發(fā)病2個月后,觀察組各組靜脈竇壓力與MBI相關(guān)性分析呈負(fù)相關(guān)。結(jié)論:利用神經(jīng)介入技術(shù)超選上矢狀竇結(jié)合多功能心電監(jiān)護儀監(jiān)測上矢狀竇壓力是一個簡單可行、風(fēng)險較低的檢查方式,可于介入檢查時一并完成,可以客觀測得上矢狀竇壓力。上矢狀竇血栓患者的臨床癥狀嚴(yán)重程度與上矢狀竇內(nèi)壓力成正相關(guān),壓力越高,患者臨床癥狀越嚴(yán)重。根據(jù)患者術(shù)后2個月后MBI神經(jīng)功能缺損評分,入院時靜脈竇壓力越高,MBI評分越低,患者預(yù)后越差。
[Abstract]:Objective: to measure the superior sagittal sinus pressure of patients with superior sagittal sinus thrombosis and negative cerebral angiography by nerve intervention technique, and to calculate the difference between superior sagittal sinus pressure and superior sagittal sinus pressure in patients with superior sagittal sinus thrombosis and patients with negative venography by neurointerventional technique, and to calculate the difference between superior sagittal sinus pressure and superior sagittal sinus pressure in patients with superior sagittal sinus thrombosis and negative cerebral angiography. To investigate the effect of superior sagittal sinus pressure on the severity of superior sagittal sinus thrombosis and the prognosis of superior sagittal sinus thrombosis. Methods: from March 2015 to October 2016, 22 patients with superior sagittal sinus thrombosis diagnosed by DSA in Hebei Provincial people's Hospital were selected as observation group, 6 males and 16 females, aged 20 鈮，

本文編號：2506176