【摘要】：目的探討狼瘡性腦病的臨床特點(diǎn)及診治 方法回顧性分析2012-2013年間我院神經(jīng)內(nèi)科收治的4例狼瘡性腦病病例資料,并結(jié)合文獻(xiàn)進(jìn)行復(fù)習(xí)。 設(shè)計(jì)病例報(bào)告 病例4例病例均為女性,年齡在27-43歲間,2例有系統(tǒng)性紅斑狼瘡病史,其余2例均為初次在我科診斷并治療。 干預(yù)4例均給予糖皮質(zhì)激素激素及免疫抑制劑治療,其中2例給予細(xì)胞毒性藥物,1例給予靜脈用丙種球蛋白及升壓、呼吸興奮劑等搶救治療。 結(jié)果3例患者康復(fù)出院,1例因病情進(jìn)行性加重,終搶救無(wú)效死亡。 結(jié)論狼瘡性腦病是系統(tǒng)性紅斑狼瘡的嚴(yán)重并發(fā)癥,死亡率較高。早期診斷,及時(shí)治療,能夠改善系統(tǒng)性紅斑狼瘡的預(yù)后,降低死亡率。
[Abstract]:Objective to investigate the clinical characteristics, diagnosis and treatment of lupus encephalopathy (Lupus Encephalopathy). To analyze the data of 4 cases of Lupus Encephalopathy treated in Department of Neurology in our hospital from 2012 to 2013, and to review the literature. All 4 cases reported in the design were female, aged between 27 years and 43 years old, 2 cases had a history of systemic lupus erythematosus, and the other 2 cases were diagnosed and treated in our department for the first time. All 4 cases were treated with glucocorticoid and immunosuppressant, 2 cases were treated with cytotoxicity drugs, 1 case was treated with intravenous gamma globulin, pressor, respiratory stimulant and so on. Results three patients recovered and discharged from hospital, 1 patient died of progressive aggravation. Conclusion Lupus Encephalopathy is a serious complication of systemic lupus erythematosus (SLE), and the mortality rate is high. Early diagnosis and timely treatment can improve the prognosis of systemic lupus erythematosus and reduce mortality.
【學(xué)位授予單位】：蘭州大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R593.241;R747.9

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本文編號(hào)：2499966