【摘要】：目的:比較不同中青年缺血性腦卒中患者的CISS分型發(fā)病的臨床特點及預后的分析。方法:收集從2011年1月-2015年11月共96例入住廣西壯族自治區(qū)人民醫(yī)院神經(jīng)內(nèi)科的18歲-59歲的缺血性腦卒中患者的人口學情況、發(fā)病后第一次入院的檢查及檢驗數(shù)據(jù),在2016年12月進行電話隨訪,分別記錄患者是否堅持腦卒中二級預防,是否留下后遺癥及mRS,是否復發(fā)或死亡;將患者進行CISS分型,分析CISS各亞型的缺血性腦卒中臨床特點,為缺血性腦卒中的預防提供幫助。結(jié)果:本次研究的結(jié)果如下:CISS分型:大動脈硬化型(large artery atherosclerosis type LAA 39例40.6%),心源性(cardiogenic stroke CS 9例9.4%),穿支動脈型(perforator artery type PAD 42例43.7%),其它病因(other etiology 4例OE4.2%)、病因不明(undetermined etiology UE 2例2.1%),CISS分型中膽紅素、房顫、年齡在組間比較有統(tǒng)計學差異(P0.05),各亞型缺血性腦卒中病死率及復發(fā)率差異無統(tǒng)計學意義(P0.05)。結(jié)論:中青年缺血性腦卒中CISS分型各亞型與高血壓、糖尿病、吸煙等及C反應蛋白、尿酸無統(tǒng)計學相關(guān),膽紅素、房顫、年齡有統(tǒng)計學相關(guān)性,不同CISS分型的臨床特點及預后無統(tǒng)計學相關(guān)性,但其中穿支動脈病變復發(fā)率和死亡率相對較高。
[Abstract]:Objective: to compare the clinical features and prognosis of CISS typing in different middle-aged and young patients with ischemic stroke. Methods: from January 2011 to November 2015, 96 patients aged 18-59 years old with ischemic stroke who were admitted to the Department of Neurology of Guangxi Zhuang Autonomous region people's Hospital were collected. A telephone follow-up was conducted in December 2016 to record whether the patients insisted on secondary prevention of stroke, whether the sequelae were left behind, and whether mRS, recurred or died. The patients were classified by CISS, and the clinical characteristics of ischemic stroke of CISS subtypes were analyzed in order to provide help for the prevention of ischemic stroke. Results: the results of this study were as follows: CISS classification: 39 cases of atherosclerotic (large artery atherosclerosis type LAA (40.6%), 9 cases of cardiogenic (cardiogenic stroke CS (9.4%), 42 cases of perforating artery type (perforator artery type PAD (43.7%). Other etiology of (other etiology 4 cases of OE4.2%, 2 cases of unknown etiology of (undetermined etiology UE 2.1%), CISS classification of bilirubin, atrial fibrillation, age was statistically different between groups (P0.05). There was no significant difference in mortality and recurrence rate of ischemic stroke among subtypes (P0.05). Conclusion: there is no significant correlation between CISS subtypes and hypertension, diabetes mellitus, smoking, C-reactive protein, uric acid, bilirubin, atrial fibrillation and age in middle-aged and young patients with ischemic stroke. There was no statistical correlation between the clinical features and prognosis of different CISS classification, but the recurrence rate and mortality rate of perforating artery disease were relatively high.
【學位授予單位】：廣西中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R743.3

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