【摘要】：目的探討Hp感染對帕金森病患者運動水平的影響,為臨床治療提供參考依據(jù)。方法選取2014年5月-2016年5月醫(yī)院住院治療的帕金森病患者96例,根據(jù)是否發(fā)生感染將患者分為Hp感染組51例和非Hp感染組45例,治療13周后,比較兩組患者的總體療效、運動水平。結(jié)果 Hp感染組患者顯效比例和總有效率顯著的高于非Hp感染組,差異有統(tǒng)計學(xué)意義(P0.05);治療后,與治療前相比,Hp感染組患者UPDRS-Ⅳ量表評分顯著降低,Hp感染組患者的UPDRS-Ⅳ量表評分顯著低于非Hp感染組,差異均有統(tǒng)計學(xué)意義(P0.05);治療前,兩組患者"開、關(guān)"期時間的差異無統(tǒng)計學(xué)意義,治療后,Hp感染組患者"開"期時間顯著長于非Hp感染組,Hp感染組患者"關(guān)"期時間顯著短于非Hp感染組,差異均有統(tǒng)計學(xué)意義(P0.05)。結(jié)論清除Hp后可以有效的提升帕金森病患者的運動水平,降低運動并發(fā)癥,延緩"開關(guān)"現(xiàn)象,并提升患者的總體療效,但是具體的作用機制尚不明確,還需進一步深入研究,為改善帕金森病患者的療效提供新的治療途徑。
[Abstract]:Objective to investigate the effect of Hp infection on the exercise level of Parkinson's disease (PD) patients and to provide reference for clinical treatment. Methods 96 patients with Parkinson's disease who were hospitalized from May 2014 to May 2016 were divided into Hp infection group (n = 51) and non-Hp infection group (n = 45). After 13 weeks of treatment, the overall efficacy of the two groups was compared. Level of movement Results the effective rate and total effective rate of Hp infection group were significantly higher than that of non-Hp infection group (P0.05). After treatment, the scores of UPDRS- 鈪，

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