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基于腎為先天之本探討常染色體顯性遺傳性腦動脈病伴皮質下梗死和白質腦病基本研究思路

發(fā)布時間:2018-11-22 12:53
【摘要】:現代中醫(yī)學認為,"腎為先天之本"與基因遺傳特異相關,腎虛為先天遺傳性疾病的關鍵病機,補腎是先天遺傳性疾病關鍵而獨特的防治手段。目前,常見的單基因遺傳性腦血管疾病常染色體顯性遺傳性腦動脈病伴皮質下梗死和白質腦病(CADASIL)缺乏特異性治療手段,嚴重危害國民健康;"腎為先天之本"探索CADASIL的發(fā)病機制、防治策略合理、可行,對保障國民身心健康發(fā)展、維護家庭與社會和諧穩(wěn)定具有重要意義。
[Abstract]:Modern Chinese medicine holds that "kidney is the root of nature" is related to gene heredity, kidney deficiency is the key pathogenesis of congenital hereditary disease, and tonifying kidney is the key and unique means of prevention and cure of congenital hereditary disease. At present, the common single gene hereditary cerebrovascular diseases, autosomal dominant cerebral artery disease with subcortical infarction and leukoencephalopathy (CADASIL) lack of specific treatment, seriously endangering national health. Based on "Kidney is the basis of nature", it is of great significance to explore the pathogenesis of CADASIL, to prevent and cure it reasonably and feasible, to ensure the development of national physical and mental health and to maintain the harmony and stability of family and society.
【作者單位】: 廣州中醫(yī)藥大學第二臨床醫(yī)學院;廣州中醫(yī)藥大學第二附屬醫(yī)院;
【基金】:廣東省自然科學基金項目(No.10151040701000064)~~
【分類號】:R743.3


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