【摘要】：目的觀察紅花黃色素聯(lián)合依達拉奉治療腦梗死的效果。方法選擇2014年1月至2016年1月于我院就診的急性腦梗塞患者256例,按照隨機數(shù)字法將患者分為研究組和對照組,各128例。對照組在常規(guī)治療的基礎上加用依達拉奉治療,研究組在對照組的基礎上加用紅花黃色素治療。觀察兩組治療前后的NIHSS評分和炎癥因子變化,以及治療效果。結果兩組治療前NIHSS評分均無統(tǒng)計學意義(P0.05);治療后兩組較治療前均有降低,且研究組下降程度高于對照組,差異有統(tǒng)計學意義(P0.05)。治療前兩組hs-CRP、IL-2、IL-8和TNF-α等水平差異無統(tǒng)計學意義(P0.05),治療后兩組均有明顯降低,且研究組比對照組下降更明顯,差異有統(tǒng)計學意義(P0.05)。研究組治療有效率為95.31%,高于對照組的83.59%,差異有統(tǒng)計學意義(P0.05)。結論紅花黃色素聯(lián)合依達拉奉治療急性腦梗塞治療效果顯著,可改善患者預后,且安全可靠。
[Abstract]:Objective to observe the effect of safflower yellow and Edaravone on cerebral infarction. Methods 256 patients with acute cerebral infarction from January 2014 to January 2016 were randomly divided into two groups: study group and control group. The control group was treated with Edaravone on the basis of routine treatment, while the study group was treated with safflower yellow pigment on the basis of the control group. The changes of NIHSS score, inflammatory factor and therapeutic effect were observed before and after treatment. Results there was no significant difference in NIHSS score between the two groups before treatment (P0.05); after treatment, the NIHSS scores in the two groups were lower than before, and the degree of decrease in the study group was higher than that in the control group, the difference was statistically significant (P0.05). There was no significant difference in the levels of hs-CRP,IL-2,IL-8 and TNF- 偽 between the two groups before treatment (P0.05). After treatment, the levels of hs-CRP,IL-2,IL-8 and TNF- 偽 in the two groups were significantly decreased, and the decrease in the study group was more obvious than that in the control group (P0.05). The effective rate of treatment in the study group was 95.31, higher than that in the control group (83.59), the difference was statistically significant (P0.05). Conclusion the combination of safflower yellow and Edaravone is effective in the treatment of acute cerebral infarction. It can improve the prognosis of patients and is safe and reliable.
【作者單位】： 江蘇省海門市人民醫(yī)院;
【分類號】：R743.33

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