【摘要】：目的關(guān)于氫質(zhì)子磁共振波譜成像技術(shù)與臨床評(píng)分評(píng)價(jià)腦梗死患者療效一致性的探討分析。方法選取我院2015年7月~2016年7月收治的腦梗死患者85例作為研究對(duì)象,分析本組患者治療前后腦代謝物N-乙�；扉T冬氨酸(NAA)與乳酸(Lac)的變化及其與臨床評(píng)分的相關(guān)性。結(jié)果磁共振波譜分析腦梗死治療前NAA/Cr值為(1.24±0.27),低于治療后的(2.75±0.16),差異有統(tǒng)計(jì)學(xué)意義(P0.05),磁共振波譜分析前Lac/Cr值為(2.31±0.21),高于治療后的(0.15±0.07),差異有統(tǒng)計(jì)學(xué)意義(P0.05)。治療前患者臨床評(píng)分為(14.4±0.81)分,高于治療后的(8.1±0.47)分,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。治療前后NAA/Cr、Lac/Cr與臨床評(píng)分之間的相關(guān)性系數(shù)r_1=-6.273,r_2=7.921。結(jié)論腦梗死患者應(yīng)用氫質(zhì)子磁共振波譜分析治療前后腦代謝產(chǎn)物變化情況能獲得與臨床評(píng)分高度一致的結(jié)果,氫質(zhì)子磁共振波譜分析在腦梗死臨床診治的應(yīng)用價(jià)值值得肯定。
[Abstract]:Objective to analyze the consistency between the hydrogen proton magnetic resonance spectroscopy (HNMR) and clinical score in evaluating the curative effect of cerebral infarction patients. Methods Eighty-five patients with cerebral infarction admitted in our hospital from July 2015 to July 2016 were selected as subjects. The changes of N- acetyl aspartate (NAA) and lactate (Lac) and their correlation with clinical score were analyzed before and after treatment. Results the NAA/Cr of cerebral infarction before treatment was (1.24 鹵0.27), lower than that after treatment (2.75 鹵0.16), the difference was statistically significant (P0.05). The Lac/Cr before MRI was (2.31 鹵0.21). Higher than after treatment (0.15 鹵0.07), the difference was statistically significant (P0.05). The clinical score of patients before treatment was (14.4 鹵0.81), higher than that after treatment (8.1 鹵0.47), the difference was statistically significant (P0.05). Correlation coefficient between NAA/Cr,Lac/Cr and clinical score before and after treatment; Conclusion the changes of brain metabolites in patients with cerebral infarction before and after treatment with proton magnetic resonance spectroscopy are in high agreement with the clinical score. The value of hydrogen proton magnetic resonance spectroscopy in the diagnosis and treatment of cerebral infarction is worthy of recognition.
【作者單位】： 內(nèi)蒙古自治區(qū)人民醫(yī)院;
【分類號(hào)】：R743.33

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