發(fā)布時(shí)間：2018-10-05 21:32

【摘要】：目的：采用頸動(dòng)脈超聲(carotid artery ultrasound)和經(jīng)顱多普勒超聲(transcranial doppler, TCD)技術(shù)聯(lián)合評(píng)價(jià)和隨訪頸動(dòng)脈狹窄患者行頸動(dòng)脈支架置入術(shù)(carotid artery stenting, CAS)的治療效果。方法：回顧分析經(jīng)全腦血管造影(digital subtraction angiography, DSA)確診具有腦缺血癥狀的頸動(dòng)脈狹窄且接受頸動(dòng)脈支架置入術(shù)治療的患者71例,采用頸動(dòng)脈超聲聯(lián)合經(jīng)顱多普勒超聲測(cè)量頸動(dòng)脈支架置入術(shù)治療前、后頸動(dòng)脈狹窄局部管徑、狹窄段收縮期峰值流速(peak systolic velocity, PSV)及同側(cè)大腦中動(dòng)脈(middle cerebral artery, MCA)的收縮期峰值流速、搏動(dòng)指數(shù)(pulsatility index, PI),并進(jìn)行對(duì)比分析。結(jié)果：頸動(dòng)脈狹窄患者行頸動(dòng)脈支架置入術(shù)后原狹窄處內(nèi)徑由術(shù)前(3.13±0.83)mm增加至術(shù)后1周的(4.77±0.51)mm(P0.05)、術(shù)后1年的(4.64±0.52)mm(P0.05)；頸動(dòng)脈狹窄處收縮期峰值流速由術(shù)前(190.69±113.65)cm/s,降至術(shù)后1周的(86.15±30.52)cm/s(P0.05)、術(shù)后1年的(90.28±29.79)cm/s(P0.05);患側(cè)MCA的收縮期峰值流速由術(shù)前(77.68±14.66)cm/s,術(shù)后1周升高為(115.62±22.32)cm/s(P0.05),術(shù)后1年升高為(108.89±20.29)cm/s(P0.05),PI值由術(shù)前0.81±0.01,術(shù)后1周提高到1.07±0.01(P0.05)、術(shù)后1年提高到1.06±0.02(P0.05)。結(jié)論：頸動(dòng)脈超聲和經(jīng)顱多普勒超聲檢測(cè)結(jié)果提示頸動(dòng)脈支架置入術(shù)后,頸動(dòng)脈血管內(nèi)徑及腦血流動(dòng)力學(xué)有明顯改善,頸動(dòng)脈超聲和經(jīng)顱多普勒超聲聯(lián)合可以作為準(zhǔn)確評(píng)價(jià)和隨訪頸動(dòng)脈支架置入術(shù)療效的有效手段。
[Abstract]:Objective: to evaluate and follow up the therapeutic effect of carotid artery stenting (carotid artery stenting, CAS) by carotid (carotid artery ultrasound) and transcranial Doppler ultrasound (transcranial doppler, TCD) in patients with carotid artery stenosis. Methods: 71 patients with carotid artery stenosis diagnosed by (digital subtraction angiography, DSA) with cerebral ischemia and treated by carotid stenting were retrospectively analyzed. Carotid artery ultrasound combined with transcranial Doppler ultrasound was used to measure the local diameter, peak systolic velocity (peak systolic velocity, PSV) of the stenosis segment and peak systolic velocity (middle cerebral artery, MCA) of the ipsilateral middle cerebral artery (MCA) before and after carotid stenting. Pulsatility index (pulsatility index, PI),) was compared and analyzed. Results: the internal diameter of the original stenosis increased from (3.13 鹵0. 83) mm to (4. 77 鹵0. 51) mm () in 1 week and (4. 64 鹵0. 52) mm () in 1 year after carotid artery stenosis. The peak systolic velocity of carotid artery stenosis decreased from (190.69 鹵113.65) cm/s, before operation to (86.15 鹵30.52) cm/s at 1 week after operation and (90.28 鹵29.79) cm/s at 1 year after operation (P0.05), and the peak systolic velocity of MCA on the affected side increased from (77.68 鹵14.66) cm/s, to (115.62 鹵22.32) cm/s (P0.05), and 1 year after operation to (108.89 鹵20.29) cm/s (P0.05). Weeks increased to 1.07 鹵0.01 (P0.05), and 1 year after operation to 1.06 鹵0.02 (P0.05). Conclusion: carotid artery diameter and cerebral hemodynamics were significantly improved after carotid stent implantation by carotid ultrasound and transcranial Doppler ultrasound. The combination of carotid ultrasound and transcranial Doppler ultrasound can be used as an effective method to evaluate and follow up the outcome of carotid stenting.
【學(xué)位授予單位】：新疆醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類(lèi)號(hào)】：R743.3

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相關(guān)期刊論文 前9條

1 王桂紅,王擁軍,姜衛(wèi)劍,杜彬,何耀,金e，

本文編號(hào)：2254939