發(fā)布時間：2018-09-08 10:58

【摘要】：目的探討多部門聯(lián)合干預(yù)規(guī)范神經(jīng)外科開顱腫瘤切除術(shù)預(yù)防性使用抗菌藥物的效果。方法通過規(guī)范手術(shù)前消毒和手術(shù)操作,以及抗菌藥物使用培訓(xùn)教育、開展品管圈活動和定期檢查反饋方式,觀察某院開顱腫瘤切除術(shù)預(yù)防性使用抗菌藥物的改進(jìn)效果。結(jié)果 2013、2014年調(diào)查的病例手術(shù)部位感染發(fā)病率分別為7.66%(17/222)和6.80%(27/397),兩組比較,差異無統(tǒng)計學(xué)意義(χ~2=0.158,P0.05)。手術(shù)病例預(yù)防性使用抗菌藥物:其中頭孢呋辛495例,頭孢唑林103例,頭孢硫咪9例,克林霉素8例,頭孢噻肟4例,用藥品種比較合理。2014年手術(shù)中必要的抗菌藥物追加落實(shí)率為95.02%,高于2013年的87.66%,兩組比較,差異有統(tǒng)計學(xué)意義(χ~2=7.969,P0.05)。2014年預(yù)防性使用抗菌藥物療程48 h的患者占30.73%,低于2013年的57.66%,差異有統(tǒng)計學(xué)意義(χ~2=42.88,P0.05)。結(jié)論規(guī)范手術(shù)前消毒和手術(shù)操作,開展教育培訓(xùn)、品管圈活動和檢查反饋等多種干預(yù)措施,可以促進(jìn)神經(jīng)外科開顱腫瘤切除術(shù)抗菌藥物的規(guī)范使用。
[Abstract]:Objective to investigate the effect of multi-department intervention on prophylactic use of antimicrobial agents in neurosurgical craniotomy. Methods through standardizing disinfection and operation before operation, training and education on the use of antimicrobial agents, conducting quality control circle activities and regular examination and feedback, the improvement effect of prophylactic use of antimicrobial agents in craniotomy was observed in a certain hospital. Results the incidence of surgical site infection in 2013 and 2014 was 7.66% (17 / 222) and 6.80% (27 / 397) respectively. There was no significant difference between the two groups (蠂 ~ (2 / 2) 0.158). There were 495 cases of cefuroxime, 103 cases of cefazolin, 9 cases of ceftaxime, 8 cases of clindamycin, 4 cases of cefotaxime. The necessary antimicrobial supplementation rate in 2014 was 95.022, which was higher than that in 2013, 87.666.The two groups were compared with each other. The difference was statistically significant (蠂 ~ 2 + 7.969). In 2014, the patients with prophylactic use of antimicrobial agents for 48 hours accounted for 30.73, lower than 57.66 in 2013 (蠂 ~ (2) 2) 42.88 (P0.05). Conclusion standardizing disinfection and operation before operation, carrying out education and training, quality control circle activity and examination feedback can promote the standardized use of antibiotics in craniotomy of neurosurgery.
【作者單位】： 廣西醫(yī)科大學(xué)第一附屬醫(yī)院;
【基金】：廣西壯族自治區(qū)衛(wèi)生廳課題(桂衛(wèi)Z2013101)
【分類號】：R739.4
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本文編號：2230320