【摘要】：目的觀察恩必普注射液聯(lián)合敏使朗治療老年急性后循環(huán)缺血(APCI)的療效,及其對成本效益的影響。方法將64例APCI患者隨機分為觀察組和對照組各32例,均給予常規(guī)對癥治療;觀察組采用恩必普注射液聯(lián)合敏使朗治療,對照組采用敏使朗治療,療程為2周。評價兩組臨床療效,取血檢測治療前后血液流變學(xué)指標(biāo),采用超聲檢測雙側(cè)椎-基底動脈血流指標(biāo),計算成本效益比(C/E)。結(jié)果觀察組總有效率90.6%,高于對照組的68.7%(P0.05);治療后兩組各血液流變學(xué)指標(biāo)均較治療前下降,且觀察組低切血黏度、紅細(xì)胞壓積及血小板聚集率低于對照組(P均0.05);治療后兩組雙側(cè)椎-基底動脈血流平均流速、收縮期峰值流速均較治療前升高,且觀察組升高幅度均大于對照組(P均0.05)。觀察組CE為65.52,高于對照組的56.29,但差異有沒有統(tǒng)計學(xué)意義。結(jié)論恩必普注射液聯(lián)合敏使朗可有效改善老年APCI患者的臨床癥狀、血液流變學(xué)及椎-基底動脈血流指標(biāo),且成本效益更好。
[Abstract]:Objective to observe the efficacy of Enpip injection combined with Minzhenlong in the treatment of aged patients with acute posterior circulation ischemia (APCI) and its effect on cost effectiveness. Methods Sixty-four patients with APCI were randomly divided into observation group (n = 32) and control group (n = 32). To evaluate the clinical effect of the two groups, to measure the hemorheology before and after treatment, and to measure the blood flow of bilateral vertebrobasilar artery by ultrasound, and to calculate the cost benefit ratio (C / E). Results the total effective rate of the observation group was 90.6%, which was higher than that of the control group (68.7%) (P0.05). Hematocrit and platelet aggregation rate were lower than those of the control group (P 0.05), the mean velocity and peak systolic velocity of the bilateral vertebrobasilar artery in both groups were higher than those before treatment, and the amplitude of increase in the observation group was higher than that in the control group (P 0.05). The CE of the observation group was 65.52, which was higher than that of the control group (56.29), but the difference was statistically significant. Conclusion Enpip injection combined with Herba can effectively improve the clinical symptoms, hemorheology and vertebrobasilar artery blood flow in elderly patients with APCI, and is more cost-effective.
【作者單位】： 蘇州大學(xué)第一附屬醫(yī)院;無錫市人民醫(yī)院;
【分類號】：R743.3

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