本文選題：高血壓 + 冠心病��； 參考：《山東大學(xué)》2014年碩士論文

【摘要】：目的：觀察單純高血壓及高血壓合并冠心病患者、高血壓合并腦梗塞患者的動(dòng)態(tài)血壓特點(diǎn),并分析掌握其規(guī)律,以指導(dǎo)降壓治療。 方法：對(duì)47例冠心病合并高血壓患者(A組)、50例腦梗塞合并高血壓患者(B組)及46例單純高血壓患者(C組)行24小時(shí)動(dòng)態(tài)血壓監(jiān)測(cè)。 結(jié)果：A、B組患者24小時(shí)平均收縮壓(24hMSBP)、24小時(shí)平均脈壓(24hMPP)、夜間平均收縮壓(nMSBP)均高于C組患者(P0.05),較后者,前兩組患者存在更高的血壓節(jié)律異常及晨峰現(xiàn)象(P0.05)。B組患者24hMSBP、24hMPP高于A組患者(P0.05),A組患者24小時(shí)平均舒張壓(24hMDBP)高于B組患者(P0.05)。A組患者血壓晨峰發(fā)生率高于B組患者(P0.05),兩組患者血壓晝夜節(jié)律比較無(wú)統(tǒng)計(jì)學(xué)差異(P0.05)。 結(jié)論： 血壓持續(xù)升高、脈壓增大、血壓晝夜節(jié)律消失及血壓晨峰現(xiàn)象是高血壓患者發(fā)生冠心病及腦梗塞的重要危險(xiǎn)因素；冠心病患者更多存在血壓晨峰；腦梗塞組患者收縮壓較冠心病組患者高,冠心病組患者舒張壓較腦梗塞組患者高。
[Abstract]:Aim: to observe the characteristics of ambulatory blood pressure (ABBP) in patients with hypertension and coronary heart disease (CHD) and hypertensive patients with cerebral infarction (CI), and to analyze and master the rules of ABP in order to guide hypotensive therapy. Methods: 24 hours ambulatory blood pressure monitoring was performed in 47 patients with coronary heart disease complicated with hypertension (group A), 50 patients with cerebral infarction with hypertension (group B) and 46 patients with simple hypertension (group C). Results 24 hours mean systolic pressure (24 h MSBP) and 24 hour mean pulse pressure (24 h MPP) in group B were higher than those in group C (P 0.05), and the mean systolic pressure at night (nMSBP) in group B were higher than those in group C (P0.05). There were higher blood pressure rhythm abnormality and morning peak phenomenon in the first two groups (P0.05). The 24 h MSBP 24h MPP in group B was higher than that in group A (P0.05). The mean 24-hour diastolic blood pressure (24 h MDBP) in group A was higher than that in group B (P0.05). The incidence of morning peak in group A was higher than that in group B (P0.05), and the incidence of morning peak in group A was higher than that in group B (P0.05). There was no significant difference in circadian rhythm of blood pressure between the two groups (P0.05). Conclusion: continuous increase of blood pressure, increase of pulse pressure, disappearance of circadian rhythm of blood pressure and morning peak of blood pressure are important risk factors for coronary heart disease and cerebral infarction in patients with hypertension, and there are more morning peaks of blood pressure in patients with coronary heart disease. Systolic blood pressure in cerebral infarction group was higher than that in coronary heart disease group, and diastolic blood pressure in coronary heart disease group was higher than that in cerebral infarction group.
【學(xué)位授予單位】：山東大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R544.1;R541.4;R743.3

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