本文選題：膠質(zhì)瘤術(shù)后 + DWI��； 參考：《寧夏醫(yī)科大學(xué)》2014年碩士論文

【摘要】：目的研究彌散加權(quán)成像（DWI）對于腦膠質(zhì)瘤術(shù)后早期缺血的診斷價值，探討膠質(zhì)瘤術(shù)后早期腦缺血的相關(guān)危險因素。 方法收集并分析8例腦膠質(zhì)瘤患者手術(shù)前后MRI、DWI，以及患者個體因素、腫瘤相關(guān)因素、手術(shù)相關(guān)因素、治療相關(guān)因素、治療效果等方面的資料。 結(jié)果8例患者，1例患者術(shù)前肢體肌力下降，，手術(shù)及藥物治療后未見明顯緩解，2例患者術(shù)后出現(xiàn)一側(cè)肢體肌力下降，其中1例經(jīng)藥物治療后恢復(fù)，另1例未完全恢復(fù)。影像學(xué)結(jié)果：1例患者術(shù)后DWI檢查上出現(xiàn)片狀高亮影，且病變累及內(nèi)囊區(qū)，2例出現(xiàn)術(shù)區(qū)邊緣少量高信號影，相應(yīng)區(qū)域ADC值測量示明顯較對側(cè)降低，ADC圖亦呈明顯低信號；1例患者術(shù)區(qū)邊緣出現(xiàn)少量混雜高信號，相應(yīng)部位ADC圖亦呈混雜稍低信號。 結(jié)論 1．DWI檢查對于膠質(zhì)瘤術(shù)后水腫及缺血等術(shù)后并發(fā)癥有重要鑒別意義。 2．膠質(zhì)瘤術(shù)后早期腦缺血DWI異常早于臨床癥狀，為術(shù)后缺血性腦梗死的預(yù)防提供了治療機會。
[Abstract]:Objective to study the diagnostic value of diffusion-weighted imaging (DWI) in early cerebral ischemia after glioma operation, and to explore the risk factors of early cerebral ischemia after glioma surgery. Methods the data of 8 patients with glioma before and after operation were collected and analyzed, including individual factors, tumor related factors, surgical factors, therapeutic effect and so on. Results the muscle strength of one patient was decreased before operation, but there was no obvious relief after operation and medication in 2 patients. One patient recovered after drug therapy, and the other one did not recover completely. The imaging results were as follows: 1 case showed flake highlight on DWI, and 2 cases with lesions involved in the internal capsule area showed a small amount of high signal intensity. The ADC value of the corresponding area was significantly lower than that of the contralateral decrease in ADC image. A small amount of mixed hyperintense signal appeared in the edge of the operation area in one patient, and the ADC map of the corresponding part also showed a slightly lower signal intensity. DWI has important significance in differentiating postoperative complications such as edema and ischemia after glioma. 2. The abnormal DWI of cerebral ischemia in early stage of glioma is earlier than that of clinical symptoms. It provides a therapeutic opportunity for the prevention of ischemic cerebral infarction after operation.
【學(xué)位授予單位】：寧夏醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號】：R739.41

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