本文選題：缺血性腦卒中 + 再發(fā)性腦卒中　； 參考：《臨床放射學(xué)雜志》2017年06期

【摘要】：目的在Essen卒中風(fēng)險(xiǎn)評分量表(ESRS)模型基礎(chǔ)上,結(jié)合頸動脈高分辨MR成像技術(shù),建立改良腦卒中風(fēng)險(xiǎn)評分模型(RSRS)。方法回顧性分析41例缺血性腦卒中(AIS)初發(fā)和再發(fā)患者的臨床及實(shí)驗(yàn)室指標(biāo),所有患者均行高分辨MR序列成像,對比初發(fā)及再發(fā)AIS患者頸動脈斑塊負(fù)荷和成分的差別,并進(jìn)行Logstic多因素回歸分析,篩選出獨(dú)立危險(xiǎn)因素并逐步構(gòu)建分層方案,聯(lián)合ESRS形成改良的RSRS,利用ROC曲線評估ESRS及RSRS預(yù)測卒中再發(fā)的準(zhǔn)確性。結(jié)果 (1)再發(fā)組與初發(fā)組AIS患者高血壓、糖尿病、低密度脂蛋白(LDL-C)、總膽固醇(TC)、標(biāo)準(zhǔn)化管壁指數(shù)(NWI)、斑塊內(nèi)出血(IPH)比例、破裂的纖維帽(FCR)比例、富含脂質(zhì)壞死核心(LRNC)最大面積/指數(shù)和IPH最大面積/指數(shù)組間差異均有統(tǒng)計(jì)學(xué)意義(P0.05)。(2)LDL-C、IPH、FCR、NWI值及LRNC指數(shù)是AIS患者發(fā)生再發(fā)腦卒中的獨(dú)立危險(xiǎn)因素。(3)ROC曲線顯示,ESRS及RSRS評分的曲線下面積分別為0.890和0.912,當(dāng)RSRS評分=6分時(shí),其敏感性及特異性最高。結(jié)論 ESRS和RSRS均對AIS再發(fā)有明確的預(yù)測價(jià)值,但改良后的RSRS預(yù)測價(jià)值更大;RSRS評分=6分可作為預(yù)測AIS再發(fā)風(fēng)險(xiǎn)的分層方案。
[Abstract]:Objective to establish a modified stroke risk scale (RSRS) based on Essen Stroke risk scale (ESRS) and carotid high resolution Mr imaging. Methods the clinical and laboratory indexes of 41 patients with ischemic stroke (AIS) were analyzed retrospectively. All patients underwent high resolution Mr sequence imaging. The carotid plaque load and composition were compared between primary and recurrent AIS patients. Logistic multivariate regression analysis was performed to screen out independent risk factors and gradually construct a stratified scheme to form improved RSRSs combined with ESRS. The accuracy of ESRS and RSRS in predicting stroke recurrence was evaluated by ROC curve. Results (1) Hypertension, diabetes, low density lipoprotein (LDL-C), total cholesterol (TC), standardized wall index (NWI), intraplaque hemorrhage (IPH), broken fibrous cap (FCR) were observed in recurrent and primary AIS patients. There were significant differences in the maximum area / index and the maximum area / index of lipid necrosis core (LRNC) between the two groups (P0.05). (P0.05) LDL-CMr FCR-NWI value and LRNC index were independent risk factors for recurrent stroke in AIS patients. (3) the ROC curve showed the ESRS and RSRS scores. The area under the curve was 0.890 and 0.912, respectively, when the RSRS score was 6, Its sensitivity and specificity are the highest. Conclusion both ESRS and RSRS have definite predictive value for AIS recurrence, but the improved RSRS score of 6 can be used to predict the recurrence risk of AIS.
【作者單位】： 福建醫(yī)科大學(xué)附屬第一醫(yī)院影像科;福建衛(wèi)生職業(yè)技術(shù)學(xué)院附屬省直機(jī)關(guān)醫(yī)院醫(yī)學(xué)影像科;
【基金】：福建省衛(wèi)生系統(tǒng)中青年骨干人才培養(yǎng)項(xiàng)目(編號:2013-ZQN-JC-12)
【分類號】：R743.3

【相似文獻(xiàn)】

中國期刊全文數(shù)據(jù)庫 前1條

1 王瑩瑩;郭娜;何金婷;邵延坤;包曉群;莽靖;徐忠信;;不同評分模型對短暫性腦缺血發(fā)作后腦梗死的風(fēng)險(xiǎn)預(yù)測價(jià)值[J];吉林大學(xué)學(xué)報(bào)(醫(yī)學(xué)版);2014年04期

，

本文編號：2069060